Bluebonnet Evening Primrose Oil 1,300 mg softgels contains 100% pure, natural cold-pressed evening primrose oil (EPO) with standardised amounts of fatty acids from omega-6 (1,076 mg/serving) and omega-9 (135 mg/serving). Evening primrose oil is derived from the seeds of the evening primrose plant known as Oenthera biennis, and they are a source of healthy fatty acids. Bluebonnet Evening Primrose Oil 1,300 mg softgels are a significant source of the unsaturated fats required for good health, such as the omega-6 essential fatty acids, linoleic acid (941 mg) and gamma linolenic acid, known as GLA (135 mg), as well as omega-9 fatty acid, oleic acid (135 mg). These fatty acids, specifically linoleic acid, are used in the biosynthesis of prostaglandins (hormone-like substances) and are incorporated into phospholipids, which are a main component of cellular membranes. GLA is a long-chain polyunsaturated fatty acid, which produces PGE-1, a prostaglandin. PGE-1 inhibits inflammation in the body by knocking out COX-2, an enzyme involved in the inflammation pathway. Inflammation can occur in different places in the body, such as the joints and skin.GLA supplementation can circumvent these problems, leading to more predictable levels of PGE-1, which aids in the inhibition of inflammation in the body. Women with premenstrual syndrome may have a deficiency of GLA; therefore, they may find evening primrose oil supplementation beneficial.