NIOD Copper Amino Isolate Serum 3 1:1 - 30ml
Introducing NIOD’s third generation, multi-award-winning Copper Amino Isolate Serum 3 1:1, a water-based serum suited to all skin types, as a replacement for the Copper Amino Isolate Serum 2:1. The high-performance formula contains a 1% concentration by weight of pre-assembled and fully stable GHK-Cu, alongside 1% GHK peptide. Plus, additional collagen-supporting peptides such as tripeptide-29, acetyl tetrapeptide-2 and trifluoro acetyl tripeptide-2 help address visible signs of ageing such as fine lines and loss of firmness. Boasting a lightweight, fluid texture, the serum intensely hydrates and nourishes thanks to a blend of mono-dispersed, plant-derived glycogen and cross-linked hyaluronic acid. The 2% concentration of GHK and GHK-Cu aims to reduce the appearance of textural irregularities and uneven tone, while minimising the look of visibly enlarged pores for radiant-looking complexion. With continued use, skin appears smooth and supple, adorned with a natural glow.
Introducing NIOD’s third generation, multi-award-winning Copper Amino Isolate Serum 3 1:1, a water-based serum suited to all skin types, as a replacement for the Copper Amino Isolate Serum 2:1. The high-performance formula contains a 1% concentration by weight of pre-assembled and fully stable GHK-Cu, alongside 1% GHK peptide. Plus, additional collagen-supporting peptides such as tripeptide-29, acetyl tetrapeptide-2 and trifluoro acetyl tripeptide-2 help address visible signs of ageing such as fine lines and loss of firmness. Boasting a lightweight, fluid texture, the serum intensely hydrates and nourishes thanks to a blend of mono-dispersed, plant-derived glycogen and cross-linked hyaluronic acid. The 2% concentration of GHK and GHK-Cu aims to reduce the appearance of textural irregularities and uneven tone, while minimising the look of visibly enlarged pores for radiant-looking complexion. With continued use, skin appears smooth and supple, adorned with a natural glow.
Introducing NIOD’s third generation, multi-award-winning Copper Amino Isolate Serum 3 1:1, a water-based serum suited to all skin types, as a replacement for the Copper Amino Isolate Serum 2:1. The high-performance formula contains a 1% concentration by weight of pre-assembled and fully stable GHK-Cu, alongside 1% GHK peptide. Plus, additional collagen-supporting peptides such as tripeptide-29, acetyl tetrapeptide-2 and trifluoro acetyl tripeptide-2 help address visible signs of ageing such as fine lines and loss of firmness. Boasting a lightweight, fluid texture, the serum intensely hydrates and nourishes thanks to a blend of mono-dispersed, plant-derived glycogen and cross-linked hyaluronic acid. The 2% concentration of GHK and GHK-Cu aims to reduce the appearance of textural irregularities and uneven tone, while minimising the look of visibly enlarged pores for radiant-looking complexion. With continued use, skin appears smooth and supple, adorned with a natural glow.
Introducing NIOD’s third generation, multi-award-winning Copper Amino Isolate Serum 3 1:1, a water-based serum suited to all skin types, as a replacement for the Copper Amino Isolate Serum 2:1. The high-performance formula contains a 1% concentration by weight of pre-assembled and fully stable GHK-Cu, alongside 1% GHK peptide. Plus, additional collagen-supporting peptides such as tripeptide-29, acetyl tetrapeptide-2 and trifluoro acetyl tripeptide-2 help address visible signs of ageing such as fine lines and loss of firmness. Boasting a lightweight, fluid texture, the serum intensely hydrates and nourishes thanks to a blend of mono-dispersed, plant-derived glycogen and cross-linked hyaluronic acid. The 2% concentration of GHK and GHK-Cu aims to reduce the appearance of textural irregularities and uneven tone, while minimising the look of visibly enlarged pores for radiant-looking complexion. With continued use, skin appears smooth and supple, adorned with a natural glow.
in 22 offers
The lowest price for NIOD Copper Amino Isolate Serum 3 1:1 - 30ml right now is $112.60 at Amazon.com.au, compared across 6 retailers.
The all-time low was $65.69 on 27 Nov 2025 — today's price is 71% above the lowest ever. It has been notably cheaper before — worth setting a price alert.
Prices last updated 25 Oct 2026.
Last updated at 25/10/2026 01:10:50
NIOD Copper Amino Isolate Serum - CAIS 3 1:1 | 15ml
Free delivery
Affiliate Disclosure: We may receive a small commission for purchases made through this link at no extra cost to you. This helps support our site. Thank you!
Niod Copper Amino Isolate Serum 3 1:1 (30ml)
Delivery between 3–6 Nov $45
NIOD Copper Amino Isolate Serum - CAIS 3 1:1 | 15ml
Delivery between 29 Oct – 2 Nov $41
NIOD Copper Amino Isolate Serum - CAIS 3 1:1 | 15ml
Free delivery between 3–6 Nov
NIOD Copper Amino Isolate Serum - CAIS 3 1:1 | 15ml
Delivery between 31 Oct – 3 Nov $29
NIOD Copper Amino Isolate Serum - CAIS 3 1:1 | 15ml
Free delivery between 3–6 Nov
originally posted on deciem.com
I've been using The Ordinary products for about a decade now and really like them, but other than Sanskipt Saponins and Hydration Vaccine, I've avoided Niod products because of the price. I decided to try some of the other Niod products during the November sale so bought this along with MMHC2, Fractionated Eye serum, and Hydration Vaccine and after using the set all together, in less than 2 months, I noticed considerable improvement in the appearance of my skin. I have pretty decent skin overall for my age (I'm 55) and have always looked younger than my age, but as I've aged, naturally, so has my skin. With this regimen, I've noticed much less wrinkling and crows feet around my eyes, they look so smooth. But the biggest difference is the area just below the corners ... MoreI've been using The Ordinary products for about a decade now and really like them, but other than Sanskipt Saponins and Hydration Vaccine, I've avoided Niod products because of the price. I decided to try some of the other Niod products during the November sale so bought this along with MMHC2, Fractionated Eye serum, and Hydration Vaccine and after using the set all together, in less than 2 months, I noticed considerable improvement in the appearance of my skin. I have pretty decent skin overall for my age (I'm 55) and have always looked younger than my age, but as I've aged, naturally, so has my skin. With this regimen, I've noticed much less wrinkling and crows feet around my eyes, they look so smooth. But the biggest difference is the area just below the corners of my mouth, on both sides. I have this pitting that has developed over time due to collagen breakdown and no matter what I've tried, nothing effects it...until now. While they haven't completely disappeared, they are so much smoother and less noticeable. I'm absolutely thrilled!My daughter has noticed a difference and in the course of two weeks, I had 3 people tell me how young I look, one of them carded me for a bar area and another guy took a double take after looking at my license and said, "I wasn't expecting that!". I have very fair skin and always have a little rosacea but now there's only a tad on the cherries of my cheeks. I would never go out without at least putting a little concealer on my problem areas (I wear minimal makeup but like to wear concealer and blush), but now, I feel comfortable enough to go without makeup if I really want or need to. I also have fair skin that is fairly sensitive so I can't wear anything with added fragrance or comedogenic ingredients, and so far haven't had any issues with pimples, acne, or clogged pores. Just really lovely smooth skin. I can't say which product is the magic pill or whether it's a synergistic effect, but regardless, I'll continue using all of these products religiously.
originally posted on deciem.com
Look like they took my review off or something cause I’m not seeing. The 1st review showing is a 5 star cancer survivor. And if you look closely most of the reviews are old. Years ago or months. The tricksters of skincare. NIOD once push itself as different, with people health at the forefront and science base with result. Now I’m questioning that. I’ve been using NIOD off and on for a min now, never paying attention to the ingredients. This copper peptide have an ingredient that should be banned from skincare. It’s a family of PFAS compounds . The ingredient is Trifluoroacetyl Tripeptide-2. Please don’t take my words for it but read about it. It’s proven to cause cancer, reproductive issues and other problems in our bodies. I’ll keep showing up until the ... MoreLook like they took my review off or something cause I’m not seeing. The 1st review showing is a 5 star cancer survivor. And if you look closely most of the reviews are old. Years ago or months. The tricksters of skincare. NIOD once push itself as different, with people health at the forefront and science base with result. Now I’m questioning that. I’ve been using NIOD off and on for a min now, never paying attention to the ingredients. This copper peptide have an ingredient that should be banned from skincare. It’s a family of PFAS compounds . The ingredient is Trifluoroacetyl Tripeptide-2. Please don’t take my words for it but read about it. It’s proven to cause cancer, reproductive issues and other problems in our bodies. I’ll keep showing up until the reformulate this productPlus it seems like the percentage is high in this product EWG scores it at 10. And that’s high.
originally posted on deciem.com
All of you who justify or don't believe the half empty bottles, consider these things: Have you bought CAIS 3 before? Have you always received a half empty bottle? NIOD also has other products in 15 ml / 30 ml bottles, have you bought some of them? Were they also half empy? I can tell you this: I have used CAIS for at least three years, and last october was the first time I received a half empty bottle. AND, in that same order last october I had with the 15 ml bottle of CAIS a bottle of FECC, and guess what? FECC was full, CAIS was half empty. The logic here is clear: the CAIS -50% campaign is BS, and Deciem was actually lying in the comments when they claimed that there is enough product and the bottle (/tube in CAIL) only is too big. Please people, use your brains ... MoreAll of you who justify or don't believe the half empty bottles, consider these things: Have you bought CAIS 3 before? Have you always received a half empty bottle? NIOD also has other products in 15 ml / 30 ml bottles, have you bought some of them? Were they also half empy? I can tell you this: I have used CAIS for at least three years, and last october was the first time I received a half empty bottle. AND, in that same order last october I had with the 15 ml bottle of CAIS a bottle of FECC, and guess what? FECC was full, CAIS was half empty. The logic here is clear: the CAIS -50% campaign is BS, and Deciem was actually lying in the comments when they claimed that there is enough product and the bottle (/tube in CAIL) only is too big. Please people, use your brains and look with your eyes and see that you're being scammed.P.S. I wanted to leave this comment immediately in october but was just too angry and disappointed. I hope this comment still reaches people. I've been using Deciem's products for many years and been extremely happy, but have now lost respect for the company since the company clearly has lost respect towards its customers and itself.
| Benefit | Reducing visible lines and wrinkles, Maintains hydration levels, Supports the skin's natural exfoliating mechanism |
| Body Part | Face |
| Form | Serum |
| Skin Type | All skin types |
| Active Ingredients | Tripeptide-29 |
NIOD Copper Amino Isolate Serum - CAIS 3 1:1 | 15ml
Free delivery
Affiliate Disclosure: We may receive a small commission for purchases made through this link at no extra cost to you. This helps support our site. Thank you!
Niod Copper Amino Isolate Serum 3 1:1 (30ml)
Delivery between 3–6 Nov $45
NIOD Copper Amino Isolate Serum - CAIS 3 1:1 | 15ml
Delivery between 29 Oct – 2 Nov $41
NIOD Copper Amino Isolate Serum - CAIS 3 1:1 | 15ml
Free delivery between 3–6 Nov
NIOD Copper Amino Isolate Serum - CAIS 3 1:1 | 15ml
Delivery between 31 Oct – 3 Nov $29
I've been using The Ordinary products for about a decade now and really like them, but other than Sanskipt Saponins and Hydration Vaccine, I've avoided Niod products because of the price. I decided to try some of the other Niod products during the November sale so bought this along with MMHC2, Fractionated Eye serum, and Hydration Vaccine and after using the set all together, in less than 2 months, I noticed considerable improvement in the appearance of my skin. I have pretty decent skin overall for my age (I'm 55) and have always looked younger than my age, but as I've aged, naturally, so has my skin. With this regimen, I've noticed much less wrinkling and crows feet around my eyes, they look so smooth. But the biggest difference is the area just below the corners ... MoreI've been using The Ordinary products for about a decade now and really like them, but other than Sanskipt Saponins and Hydration Vaccine, I've avoided Niod products because of the price. I decided to try some of the other Niod products during the November sale so bought this along with MMHC2, Fractionated Eye serum, and Hydration Vaccine and after using the set all together, in less than 2 months, I noticed considerable improvement in the appearance of my skin. I have pretty decent skin overall for my age (I'm 55) and have always looked younger than my age, but as I've aged, naturally, so has my skin. With this regimen, I've noticed much less wrinkling and crows feet around my eyes, they look so smooth. But the biggest difference is the area just below the corners of my mouth, on both sides. I have this pitting that has developed over time due to collagen breakdown and no matter what I've tried, nothing effects it...until now. While they haven't completely disappeared, they are so much smoother and less noticeable. I'm absolutely thrilled!My daughter has noticed a difference and in the course of two weeks, I had 3 people tell me how young I look, one of them carded me for a bar area and another guy took a double take after looking at my license and said, "I wasn't expecting that!". I have very fair skin and always have a little rosacea but now there's only a tad on the cherries of my cheeks. I would never go out without at least putting a little concealer on my problem areas (I wear minimal makeup but like to wear concealer and blush), but now, I feel comfortable enough to go without makeup if I really want or need to. I also have fair skin that is fairly sensitive so I can't wear anything with added fragrance or comedogenic ingredients, and so far haven't had any issues with pimples, acne, or clogged pores. Just really lovely smooth skin. I can't say which product is the magic pill or whether it's a synergistic effect, but regardless, I'll continue using all of these products religiously.
Look like they took my review off or something cause I’m not seeing. The 1st review showing is a 5 star cancer survivor. And if you look closely most of the reviews are old. Years ago or months. The tricksters of skincare. NIOD once push itself as different, with people health at the forefront and science base with result. Now I’m questioning that. I’ve been using NIOD off and on for a min now, never paying attention to the ingredients. This copper peptide have an ingredient that should be banned from skincare. It’s a family of PFAS compounds . The ingredient is Trifluoroacetyl Tripeptide-2. Please don’t take my words for it but read about it. It’s proven to cause cancer, reproductive issues and other problems in our bodies. I’ll keep showing up until the ... MoreLook like they took my review off or something cause I’m not seeing. The 1st review showing is a 5 star cancer survivor. And if you look closely most of the reviews are old. Years ago or months. The tricksters of skincare. NIOD once push itself as different, with people health at the forefront and science base with result. Now I’m questioning that. I’ve been using NIOD off and on for a min now, never paying attention to the ingredients. This copper peptide have an ingredient that should be banned from skincare. It’s a family of PFAS compounds . The ingredient is Trifluoroacetyl Tripeptide-2. Please don’t take my words for it but read about it. It’s proven to cause cancer, reproductive issues and other problems in our bodies. I’ll keep showing up until the reformulate this productPlus it seems like the percentage is high in this product EWG scores it at 10. And that’s high.
All of you who justify or don't believe the half empty bottles, consider these things: Have you bought CAIS 3 before? Have you always received a half empty bottle? NIOD also has other products in 15 ml / 30 ml bottles, have you bought some of them? Were they also half empy? I can tell you this: I have used CAIS for at least three years, and last october was the first time I received a half empty bottle. AND, in that same order last october I had with the 15 ml bottle of CAIS a bottle of FECC, and guess what? FECC was full, CAIS was half empty. The logic here is clear: the CAIS -50% campaign is BS, and Deciem was actually lying in the comments when they claimed that there is enough product and the bottle (/tube in CAIL) only is too big. Please people, use your brains ... MoreAll of you who justify or don't believe the half empty bottles, consider these things: Have you bought CAIS 3 before? Have you always received a half empty bottle? NIOD also has other products in 15 ml / 30 ml bottles, have you bought some of them? Were they also half empy? I can tell you this: I have used CAIS for at least three years, and last october was the first time I received a half empty bottle. AND, in that same order last october I had with the 15 ml bottle of CAIS a bottle of FECC, and guess what? FECC was full, CAIS was half empty. The logic here is clear: the CAIS -50% campaign is BS, and Deciem was actually lying in the comments when they claimed that there is enough product and the bottle (/tube in CAIL) only is too big. Please people, use your brains and look with your eyes and see that you're being scammed.P.S. I wanted to leave this comment immediately in october but was just too angry and disappointed. I hope this comment still reaches people. I've been using Deciem's products for many years and been extremely happy, but have now lost respect for the company since the company clearly has lost respect towards its customers and itself.
This has been a constant repurchase for 4 years as it adds a fresh young glow to my sensitive mature skin. Never caused irritation. I have tried 4 copper peptides and this is one with the most impact for me. I didn’t see results till after 3 months (skin cycle slows down with age) so I’m glad I purchased the full size. I was already using retinoids for years and this is a great addition. Retinoids in the PM, Copper peptides in AM. I highly recommend getting the full size. When I don’t use it my skin becomes dull less plump and more hyperpigmentation
My financial situation has gotten better and I can afford better skincare . Last fall I shelled for this serum, let me tell you, everytime I look at it my skin breaks out. I first got some Flavanone mud and that cleared all the congestion I had accumulated from using a substandard face wash for years. I had always been a fan of SOD mist but I couldn't afford it. Now I can, bumped that into my routine. Got some of this serum and a few good others (Crystal Retinal Serum from another company etc) and my skincare game has seriously leveled up. When I was younger, I could get away with using drugstore stuff. I am a mature woman, I need some quality in my life. Simpler routines and skincare that works. Here it is. This serum and a few other things are all one needs for ... MoreMy financial situation has gotten better and I can afford better skincare . Last fall I shelled for this serum, let me tell you, everytime I look at it my skin breaks out. I first got some Flavanone mud and that cleared all the congestion I had accumulated from using a substandard face wash for years. I had always been a fan of SOD mist but I couldn't afford it. Now I can, bumped that into my routine. Got some of this serum and a few good others (Crystal Retinal Serum from another company etc) and my skincare game has seriously leveled up. When I was younger, I could get away with using drugstore stuff. I am a mature woman, I need some quality in my life. Simpler routines and skincare that works. Here it is. This serum and a few other things are all one needs for healthy skin. Spend the money on the fewer, better things and get better results.
I purchased 4 products during the November sale - 2 CAIS, 1 mist, and 1 mud mask. I was so excited to try this brand. I started using the CAIS serum at the end of December ( 3 weeks after I purchased it) and after a week there were massive breakouts on my forehead. I came to the comment section to see if other people are experiencing this and I noticed that people who purchased CAIS during the November sale (like me) were complaining that their products arrived with an expiry date sometime in January, They were sold serums with 2 months remaining shelf life. Then I checked my serums and it turned out that there is no expiry date on their packages. No expiry date on the box or the bottle. What product did they send me? Am I using an old bad product on my skin? I ... MoreI purchased 4 products during the November sale - 2 CAIS, 1 mist, and 1 mud mask. I was so excited to try this brand. I started using the CAIS serum at the end of December ( 3 weeks after I purchased it) and after a week there were massive breakouts on my forehead. I came to the comment section to see if other people are experiencing this and I noticed that people who purchased CAIS during the November sale (like me) were complaining that their products arrived with an expiry date sometime in January, They were sold serums with 2 months remaining shelf life. Then I checked my serums and it turned out that there is no expiry date on their packages. No expiry date on the box or the bottle. What product did they send me? Am I using an old bad product on my skin? I emailed them to express my concerns and request a refund for the 2 serums and a week later I still have not heard back from them. I cannot believe that they are selling cosmetics with no expiry date. This can be a huge health hazard and this is beyond irresponsible. I would never use them again. You can keep my 100 euros NIOD to pay for our non-existent customer service. AVOID THIS SCAM at all costs and don't fall for their so-called "promotions".
A lot of the recent reviews are about product amount in the bottle so I thought I would just add one on the product itself. I have late 40's skin and have used this intermittently over last year. Last month or so I realised I needed to use up this bottle so started using day and night....and have realised suddenly how good my skin is looking. It's hard to put my finger on it.just less noticeably old and wrinkly! Someone yesterday was raving about how good my skin looked and were shocked at my age! I was a bit taken aback. Nothing is miraculous but I do think this has made a difference. Also use the HV and eye FECC with a tinted mineral SPF and a smear of photography fluid on top on my cheeks. Makes my skin look great. Not bad for an old bird!
I decided to write about my experience since a lot of people have been commenting about receiving products that are missing content, which I found concerning at the time of ordering.I first ordered the smaller bottle and sure enough, there was a lot of empty space in the bottle and the liquid didn't even reach the top of the label. However, I poured the product into a 15mL measuring spoon and the product reached the top of the measure. After this, I felt confident enough to order a couple bigger bottles, and those are basically filled to the top.So in my experience, the issue seems to be that the smaller bottles are actually just a bit bigger than 15mL in volume, so they don't get full when filled with 15mL of product. However, you are still getting the 15mL of ... MoreI decided to write about my experience since a lot of people have been commenting about receiving products that are missing content, which I found concerning at the time of ordering.I first ordered the smaller bottle and sure enough, there was a lot of empty space in the bottle and the liquid didn't even reach the top of the label. However, I poured the product into a 15mL measuring spoon and the product reached the top of the measure. After this, I felt confident enough to order a couple bigger bottles, and those are basically filled to the top.So in my experience, the issue seems to be that the smaller bottles are actually just a bit bigger than 15mL in volume, so they don't get full when filled with 15mL of product. However, you are still getting the 15mL of product in them.
As another reviewer said, CAIS3 has Trifluoroacetyl Tripeptide-2 (TFTP-2) which belongs to a very toxic group of chemicals that is linked to cancer, miscarriages and more. I have been using CAIS since version 1 and didn't bother checking the ingredients since version 1 because I trusted NIOD by default. I am a die hard CAIS and would be sad to having to stop using it and find a new replacement product. NOID team, please change the formula and please do not compromise quality and consumer's health.TFTP-2 "has high concerns for skin use restrictions, persistence and bioaccumulation, cancer, allergies and immunotoxicity, and developmental and reproductive toxicity. It also has moderate concerns for endocrine disruption and non-reproductive organ system toxicity. Some ... MoreAs another reviewer said, CAIS3 has Trifluoroacetyl Tripeptide-2 (TFTP-2) which belongs to a very toxic group of chemicals that is linked to cancer, miscarriages and more. I have been using CAIS since version 1 and didn't bother checking the ingredients since version 1 because I trusted NIOD by default. I am a die hard CAIS and would be sad to having to stop using it and find a new replacement product. NOID team, please change the formula and please do not compromise quality and consumer's health.TFTP-2 "has high concerns for skin use restrictions, persistence and bioaccumulation, cancer, allergies and immunotoxicity, and developmental and reproductive toxicity. It also has moderate concerns for endocrine disruption and non-reproductive organ system toxicity. Some say that TFTP-2 belongs to a class of chemicals called PFAS, or "forever chemicals," that can build up in the body and cause cancer."
I love the serum, and thought this would be I serum I’ll stick with until I took time to study each ingredients. I’m an engineer not a doctor nor scientist but love to read science papers. NIOD have a way with words and I can see how easy it is to be drawn in. CAIS has an ingredient that should be out and be replaced in my opinion. That ingredient is Trifluoroacetyl Tripeptide-2. It belongs to a very toxic group of chemicals that’s link to cancer, miscarriages and more. I very disappointed that NIOD would add this controversial ingredient in their products. For this reason I won’t buy this again. And to NIOD team please reformulate and don’t put our health in jeopardy for profit gains.
| Benefit | Reducing visible lines and wrinkles, Maintains hydration levels, Supports the skin's natural exfoliating mechanism |
| Body Part | Face |
| Form | Serum |
| Skin Type | All skin types |
| Active Ingredients | Tripeptide-29 |
