Advanced Clinicals 5% Niacinamide Serum Professional Strength 1.75 fl oz (52 ml)
Advanced Clinicals 5% Niacinamide Serum 52ml Infused with potent anti-aging minerals like Zinc and Magnesium. Discover bright, soft and supple skin with the antioxidant power of Niacinamide. This anti-aging form of Vitamin B erases the look of blotchy discolorations and age spots. Ultra-hydrating formula quells red spots and soothes dry areas. Our Potent 5% Niacinamide pairs up with hydrating Hyaluronic Acid, antioxidant Ferulic Acid and soothing Zinc to fight the visible signs of aging. Niacinamide targets melanin to promote a brighter complexion while Hyaluronic Acid draws moisture to dry skin, delivering a visible plumping effect. Dermatologist and allergy tested, free from parabens, dyes, and fragrance.
Advanced Clinicals 5% Niacinamide Serum 52ml Infused with potent anti-aging minerals like Zinc and Magnesium. Discover bright, soft and supple skin with the antioxidant power of Niacinamide. This anti-aging form of Vitamin B erases the look of blotchy discolorations and age spots. Ultra-hydrating formula quells red spots and soothes dry areas. Our Potent 5% Niacinamide pairs up with hydrating Hyaluronic Acid, antioxidant Ferulic Acid and soothing Zinc to fight the visible signs of aging. Niacinamide targets melanin to promote a brighter complexion while Hyaluronic Acid draws moisture to dry skin, delivering a visible plumping effect. Dermatologist and allergy tested, free from parabens, dyes, and fragrance.
Advanced Clinicals 5% Niacinamide Serum 52ml Infused with potent anti-aging minerals like Zinc and Magnesium. Discover bright, soft and supple skin with the antioxidant power of Niacinamide. This anti-aging form of Vitamin B erases the look of blotchy discolorations and age spots. Ultra-hydrating formula quells red spots and soothes dry areas. Our Potent 5% Niacinamide pairs up with hydrating Hyaluronic Acid, antioxidant Ferulic Acid and soothing Zinc to fight the visible signs of aging. Niacinamide targets melanin to promote a brighter complexion while Hyaluronic Acid draws moisture to dry skin, delivering a visible plumping effect. Dermatologist and allergy tested, free from parabens, dyes, and fragrance.
Advanced Clinicals 5% Niacinamide Serum 52ml Infused with potent anti-aging minerals like Zinc and Magnesium. Discover bright, soft and supple skin with the antioxidant power of Niacinamide. This anti-aging form of Vitamin B erases the look of blotchy discolorations and age spots. Ultra-hydrating formula quells red spots and soothes dry areas. Our Potent 5% Niacinamide pairs up with hydrating Hyaluronic Acid, antioxidant Ferulic Acid and soothing Zinc to fight the visible signs of aging. Niacinamide targets melanin to promote a brighter complexion while Hyaluronic Acid draws moisture to dry skin, delivering a visible plumping effect. Dermatologist and allergy tested, free from parabens, dyes, and fragrance.
in 3 offers
The lowest price for Advanced Clinicals 5% Niacinamide Serum Professional Strength 1.75 fl oz (52 ml) right now is $18.49 at iHerb, compared across 3 retailers.
The all-time low was $13.99 on 18 Dec 2025 — today's price is 32% above the lowest ever. It has been notably cheaper before — worth setting a price alert.
Prices last updated 9 June 2026.
Last updated at 09/06/2026 18:06:37
Advanced Clinicals, 5% Niacinamide Serum, 1.75 fl oz (52 ml)
Delivery $40
Advanced Clinicals, 5% Niacinamide Serum, Professional Strength, 1.75 fl oz (52 ml)
Delivery $14.95
Advanced Clinicals, 5% Niacinamide Serum, Professional Strength, 1.75 fl oz (52 ml)
Delivery $14.95
originally posted on walmart.com
I am going to cover all of the Advanced Clinicals serums in this one review. I use them all. They also have some wonderful sprays like Vit C with ferulic acid. When they have a sale, I really stock up. I have tried a lot of the expensive brands from my plastic surgeon's office and they are wonderful but the cost of one bottle will buy the entire Clinicals serums. The trick is to be consistent. Have a routine where you use the niniacide one night and the pepside the next night. But always start with your Vit C and finish with your hydraloic ( misspelled) acid which keeps a lot of moisture in your skin. Never go to bed with your makeup on, and drink more water than you think you can. Any moisturizer is better than nothing if you are consistent. You will be very ... MoreI am going to cover all of the Advanced Clinicals serums in this one review. I use them all. They also have some wonderful sprays like Vit C with ferulic acid. When they have a sale, I really stock up. I have tried a lot of the expensive brands from my plastic surgeon's office and they are wonderful but the cost of one bottle will buy the entire Clinicals serums. The trick is to be consistent. Have a routine where you use the niniacide one night and the pepside the next night. But always start with your Vit C and finish with your hydraloic ( misspelled) acid which keeps a lot of moisture in your skin. Never go to bed with your makeup on, and drink more water than you think you can. Any moisturizer is better than nothing if you are consistent. You will be very pleased if you start a routine with the Advanced Clinicals line of products. I have a clear shoebox size container and I make sure I order a new bottle before I run out of each product. Order online, it is much easier.You only need a dropper full of the product you are using that night. It is the most inexpensive line of products you are going to find that actually works. P
originally posted on iherb.com
Dermatologist & Allergy TestedErase Blotchy Looking SkinUnlock A Bright, Youthful GlowRapid Hydrator Diminishes the Look of Lines and WrinklesDiscover bright, soft and supple skin with the antioxidant power of Niacinamide. This anti-aging form of Vitamin B erases the look of blotchy discolorations and age spots.Ultra-hydrating formula quells red spots and soothes dry areas.Infused with potent anti-aging minerals like Zinc and Magnesium.BenefitsDark spots, blotchy tones, redness and uneven textures diminish in appearance.Leaves skin with a satin-smooth, hydrated finish that looks plumped from within.AttributesAntioxidant Niacinamide, an anti-aging form of Vitamin B, erases the look of blotchy discolorations and age spots.Infused with potent ... MoreDermatologist & Allergy TestedErase Blotchy Looking SkinUnlock A Bright, Youthful GlowRapid Hydrator Diminishes the Look of Lines and WrinklesDiscover bright, soft and supple skin with the antioxidant power of Niacinamide. This anti-aging form of Vitamin B erases the look of blotchy discolorations and age spots.Ultra-hydrating formula quells red spots and soothes dry areas.Infused with potent anti-aging minerals like Zinc and Magnesium.BenefitsDark spots, blotchy tones, redness and uneven textures diminish in appearance.Leaves skin with a satin-smooth, hydrated finish that looks plumped from within.AttributesAntioxidant Niacinamide, an anti-aging form of Vitamin B, erases the look of blotchy discolorations and age spots.Infused with potent anti-aging minerals like Zinc and Magnesium.Clinically Tested and Non-IrritatingTechnologyPotent 5% Niacinamide pairs up with hydrating Hyaluronic Acid, antioxidant Ferulic Acid and soothing Zinc to fight the visible signs of aging.Niacinamide targets melanin to promote a brighter complexion while Hyaluronic Acid draws moisture to dry skin, delivering a visible plumping effect.ResultsInstantly: Boosts skin hydration and suppleness.Within days: Skin looks more even and feels hydrated and cushiony.Within weeks: Lifts the look of discolorations and blotchy tones.
originally posted on iherb.com
combined with Niacinamide, the effects the next day is miraculous enough to lessen the itch and redness caused by hormonal acne. everytime I got stress to something, a couple of hours later and poof, one or two pimple is saying hello to my jaw area. it's really annoying and uncomfortable. my two guy friends who are vain enough told me that use glycolic and niacinamide and since I've been using advanced Clinicals then why not. never thought it will helps me in most ways. quality and size wise, I am very happy with advanced Clinicals. also for people with sensitive skin, advance clinicals is a good brand to try. I'm using this combo every other day and vitamin c+hyaluronic serum the next then retinol+hyaluronic next. I'm a 34 yo female with acne problem and Advanced ... Morecombined with Niacinamide, the effects the next day is miraculous enough to lessen the itch and redness caused by hormonal acne. everytime I got stress to something, a couple of hours later and poof, one or two pimple is saying hello to my jaw area. it's really annoying and uncomfortable. my two guy friends who are vain enough told me that use glycolic and niacinamide and since I've been using advanced Clinicals then why not. never thought it will helps me in most ways. quality and size wise, I am very happy with advanced Clinicals. also for people with sensitive skin, advance clinicals is a good brand to try. I'm using this combo every other day and vitamin c+hyaluronic serum the next then retinol+hyaluronic next. I'm a 34 yo female with acne problem and Advanced Clinicals products is gentle enough to my skin and wallet as well.
| Best By | January 2027 |
| Dimensions | 14.9 x 7.2 x 7.7 cm , 0.15 kg |
Advanced Clinicals, 5% Niacinamide Serum, 1.75 fl oz (52 ml)
Delivery $40
Advanced Clinicals, 5% Niacinamide Serum, Professional Strength, 1.75 fl oz (52 ml)
Delivery $14.95
Advanced Clinicals, 5% Niacinamide Serum, Professional Strength, 1.75 fl oz (52 ml)
Delivery $14.95
I am going to cover all of the Advanced Clinicals serums in this one review. I use them all. They also have some wonderful sprays like Vit C with ferulic acid. When they have a sale, I really stock up. I have tried a lot of the expensive brands from my plastic surgeon's office and they are wonderful but the cost of one bottle will buy the entire Clinicals serums. The trick is to be consistent. Have a routine where you use the niniacide one night and the pepside the next night. But always start with your Vit C and finish with your hydraloic ( misspelled) acid which keeps a lot of moisture in your skin. Never go to bed with your makeup on, and drink more water than you think you can. Any moisturizer is better than nothing if you are consistent. You will be very ... MoreI am going to cover all of the Advanced Clinicals serums in this one review. I use them all. They also have some wonderful sprays like Vit C with ferulic acid. When they have a sale, I really stock up. I have tried a lot of the expensive brands from my plastic surgeon's office and they are wonderful but the cost of one bottle will buy the entire Clinicals serums. The trick is to be consistent. Have a routine where you use the niniacide one night and the pepside the next night. But always start with your Vit C and finish with your hydraloic ( misspelled) acid which keeps a lot of moisture in your skin. Never go to bed with your makeup on, and drink more water than you think you can. Any moisturizer is better than nothing if you are consistent. You will be very pleased if you start a routine with the Advanced Clinicals line of products. I have a clear shoebox size container and I make sure I order a new bottle before I run out of each product. Order online, it is much easier.You only need a dropper full of the product you are using that night. It is the most inexpensive line of products you are going to find that actually works. P
Dermatologist & Allergy TestedErase Blotchy Looking SkinUnlock A Bright, Youthful GlowRapid Hydrator Diminishes the Look of Lines and WrinklesDiscover bright, soft and supple skin with the antioxidant power of Niacinamide. This anti-aging form of Vitamin B erases the look of blotchy discolorations and age spots.Ultra-hydrating formula quells red spots and soothes dry areas.Infused with potent anti-aging minerals like Zinc and Magnesium.BenefitsDark spots, blotchy tones, redness and uneven textures diminish in appearance.Leaves skin with a satin-smooth, hydrated finish that looks plumped from within.AttributesAntioxidant Niacinamide, an anti-aging form of Vitamin B, erases the look of blotchy discolorations and age spots.Infused with potent ... MoreDermatologist & Allergy TestedErase Blotchy Looking SkinUnlock A Bright, Youthful GlowRapid Hydrator Diminishes the Look of Lines and WrinklesDiscover bright, soft and supple skin with the antioxidant power of Niacinamide. This anti-aging form of Vitamin B erases the look of blotchy discolorations and age spots.Ultra-hydrating formula quells red spots and soothes dry areas.Infused with potent anti-aging minerals like Zinc and Magnesium.BenefitsDark spots, blotchy tones, redness and uneven textures diminish in appearance.Leaves skin with a satin-smooth, hydrated finish that looks plumped from within.AttributesAntioxidant Niacinamide, an anti-aging form of Vitamin B, erases the look of blotchy discolorations and age spots.Infused with potent anti-aging minerals like Zinc and Magnesium.Clinically Tested and Non-IrritatingTechnologyPotent 5% Niacinamide pairs up with hydrating Hyaluronic Acid, antioxidant Ferulic Acid and soothing Zinc to fight the visible signs of aging.Niacinamide targets melanin to promote a brighter complexion while Hyaluronic Acid draws moisture to dry skin, delivering a visible plumping effect.ResultsInstantly: Boosts skin hydration and suppleness.Within days: Skin looks more even and feels hydrated and cushiony.Within weeks: Lifts the look of discolorations and blotchy tones.
combined with Niacinamide, the effects the next day is miraculous enough to lessen the itch and redness caused by hormonal acne. everytime I got stress to something, a couple of hours later and poof, one or two pimple is saying hello to my jaw area. it's really annoying and uncomfortable. my two guy friends who are vain enough told me that use glycolic and niacinamide and since I've been using advanced Clinicals then why not. never thought it will helps me in most ways. quality and size wise, I am very happy with advanced Clinicals. also for people with sensitive skin, advance clinicals is a good brand to try. I'm using this combo every other day and vitamin c+hyaluronic serum the next then retinol+hyaluronic next. I'm a 34 yo female with acne problem and Advanced ... Morecombined with Niacinamide, the effects the next day is miraculous enough to lessen the itch and redness caused by hormonal acne. everytime I got stress to something, a couple of hours later and poof, one or two pimple is saying hello to my jaw area. it's really annoying and uncomfortable. my two guy friends who are vain enough told me that use glycolic and niacinamide and since I've been using advanced Clinicals then why not. never thought it will helps me in most ways. quality and size wise, I am very happy with advanced Clinicals. also for people with sensitive skin, advance clinicals is a good brand to try. I'm using this combo every other day and vitamin c+hyaluronic serum the next then retinol+hyaluronic next. I'm a 34 yo female with acne problem and Advanced Clinicals products is gentle enough to my skin and wallet as well.
I decided to give this a try. After finishing one bottle of this serum my skin definitely looks much better. I have rosacea and my skin has calmed down significantly. I was not happy with the large pores I saw on my face and it has had a dramatic effect on my pores. I did not have high expectations because I have spent a lot of money on a lot of products over the years to improve my complexion.I don’t notice any scent, which is good in my opinion. I use is as directed by putting it on my palms and gently rubbing my hands together and then patting it all over my face. I go up to my forehead and down to my neck. It feels a bit sticky for a few seconds and then it is absorbed. After I apply the Niacinamide I apply my moisturizer for added moisture. I am in my 70’s and ... MoreI decided to give this a try. After finishing one bottle of this serum my skin definitely looks much better. I have rosacea and my skin has calmed down significantly. I was not happy with the large pores I saw on my face and it has had a dramatic effect on my pores. I did not have high expectations because I have spent a lot of money on a lot of products over the years to improve my complexion.I don’t notice any scent, which is good in my opinion. I use is as directed by putting it on my palms and gently rubbing my hands together and then patting it all over my face. I go up to my forehead and down to my neck. It feels a bit sticky for a few seconds and then it is absorbed. After I apply the Niacinamide I apply my moisturizer for added moisture. I am in my 70’s and so I can’t really over moisturize at this point. It has aLao evened out my skin tone. I am definitely not going to stop using it.The last thing I want to say is the pump worked very well. I usually hate pumps because I can’t get the last drop out. But this bottle was totally empty last night. I panicked and will be sure not to run out again. Thankfully iHerb has amazingly fast delivery.
After my first use, I got really scared because i started getting massive red spots on my face and horrible little bumps everywhere. I thought it was the product's fault but found out this happens with all new skincare, and is called purging. After staying consistent with spot treatment and moisturizing while using, I can safely say I love this product.It absorbs well, is very easy to use and has a good amount of product for the price. I will say, it does have a slightly unpleasant smell, but this goes away very quickly when topped with a moisturizer or sunscreen, and isn't even noticeable after drying. My skin has genuinely never felt so soft and smooth in my life, and I'm so happy I stuck it out for the purging. Will absolutely be repurchasing when I finish the ... MoreAfter my first use, I got really scared because i started getting massive red spots on my face and horrible little bumps everywhere. I thought it was the product's fault but found out this happens with all new skincare, and is called purging. After staying consistent with spot treatment and moisturizing while using, I can safely say I love this product.It absorbs well, is very easy to use and has a good amount of product for the price. I will say, it does have a slightly unpleasant smell, but this goes away very quickly when topped with a moisturizer or sunscreen, and isn't even noticeable after drying. My skin has genuinely never felt so soft and smooth in my life, and I'm so happy I stuck it out for the purging. Will absolutely be repurchasing when I finish the serum! I don't have a photo to show but trust me when I say that this serum took my skin from horrible to silky smooth!For reference: I have quite dry and sensitive skin, so I'm not sure how it would react to someone with oilier, more thicker skin. But if you're like me, I recommend this product highly!
Advanced Clinicals' 5% Niacinamide Serum has been a transformative addition to my skincare routine! Having struggled with uneven skin tone and texture, I was on the lookout for a product that would provide real results without breaking the bank. This serum did not disappoint. Within just a few applications, I began to notice my skin becoming smoother, brighter, and more refined. The consistency is perfect - lightweight yet deeply hydrating, and it layers beautifully under my moisturizer. The fact that it addresses multiple skin concerns with just one potent ingredient is truly impressive. For anyone seeking a skin boost, I wholeheartedly endorse this serum. A true skincare gem!
Good qualityGood ingredientScent goodGood smellHigh careGood scent that easy use with high quality and full size18 age no package with wow benefit and composition low sensitive and gentle low frequency concernHigh ingredient dosageTaste wowEasy useGood sizeGood packageBenefit wowAgeServing easyFrequency easyGood dietFlavor good
| Best By | January 2027 |
| Dimensions | 14.9 x 7.2 x 7.7 cm , 0.15 kg |
