Age Intervention Retinol Plus redefines expectations for retinoids. Highly concentrated all-trans-retinol is combined with advanced peptides and antioxidants for maximum results and satisfaction while integrated soothing and hydrating ingredients offer superior experience with minimal acclimation. Our retinol night cream is suitable for all skin types. Apply product sparingly over entire face every other evening for the first 1-2 weeks, then slowly increase usage, as tolerated, to 1-2 times daily. If irritation occurs, decrease the frequency of application to allow the skin greater time to acclimate.