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La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml
La Roche Posay Substiane + Anti-aging Replenishing Care 40ml

La Roche Posay Substiane + Anti-aging Replenishing Care 40ml

$38.05

(654 reviews)

The Substiane cream by La Roche-Posay 40ml contains Linactyl and Pro-Xylan, a restorative complex that targets the fundamental dermis to reactivate the cells of support of the skin's fabrics. It also contains Neurosensine, to neutralize the factors of acceleration of the sensitive eyes ageing. Skin is comfortable and radiant again. Day by day, it is filled up, shaped up, and the skin's elasticity is reinforced.

The Substiane cream by La Roche-Posay 40ml contains Linactyl and Pro-Xylan, a restorative complex that targets the fundamental dermis to reactivate the cells of support of the skin's fabrics. It also contains Neurosensine, to neutralize the factors of acceleration of the sensitive eyes ageing. Skin is comfortable and radiant again. Day by day, it is filled up, shaped up, and the skin's elasticity is reinforced.

La Roche Posay Substiane + Anti-aging Replenishing Care 40ml

(654 reviews)

The Substiane cream by La Roche-Posay 40ml contains Linactyl and Pro-Xylan, a restorative complex that targets the fundamental dermis to reactivate the cells of support of the skin's fabrics. It also contains Neurosensine, to neutralize the factors of acceleration of the sensitive eyes ageing. Skin is comfortable and radiant again. Day by day, it is filled up, shaped up, and the skin's elasticity is reinforced.

The Substiane cream by La Roche-Posay 40ml contains Linactyl and Pro-Xylan, a restorative complex that targets the fundamental dermis to reactivate the cells of support of the skin's fabrics. It also contains Neurosensine, to neutralize the factors of acceleration of the sensitive eyes ageing. Skin is comfortable and radiant again. Day by day, it is filled up, shaped up, and the skin's elasticity is reinforced.

$38.05 - $168.00

in 13 offers

The lowest price for La Roche Posay Substiane + Anti-aging Replenishing Care 40ml right now is $38.05 at Fresh Beauty Co., compared across 10 retailers.

The all-time low was $38.05 on 11 Apr 2026. That's the lowest price we've ever tracked — a great time to buy.

Prices last updated 2 Sept 2026.

Size:

XL Product 40 ml

Price comparison

Price data powered by pricesAPI.io

Last updated at 02/09/2026 03:16:00

Please note: price history and price alerts are not available for some stores, including Amazon.com.au.
https://www.google.com/s2/favicons?domain=freshbeautyco.com.au&sz=64Fresh Beauty Co.

$38.05

La Roche Posay Substiane Visible Density And Volume Replenishing Care (Exp. Date: 06/2023) 40ml/1.35oz

Delivery between 8–16 Sept $8.95

https://www.google.com/s2/favicons?domain=freshbeautyco.com.au&sz=64Fresh Beauty Co.

$76.60

La Roche Posay Substiane Visible Density And Volume Replenishing Care 40ml/1.35oz

Delivery between 8–16 Sept $8.95

https://www.google.com/s2/favicons?domain=freshbeautyco.com.au&sz=64Fresh Beauty Co.

$83.20

La Roche Posay Substiane [+] Anti-Aging Replenishing Care 40ml/1.35oz

Delivery between 7–15 Sept $8.95

https://www.google.com/s2/favicons?domain=skinlovers.com&sz=64skinlovers.com

$51.48

La Roche-Posay Substiane Cream 40ml

Delivery between 9–11 Sept $10.34

https://www.google.com/s2/favicons?domain=soin-et-nature.com&sz=64Soin et Nature

$68.93

La Roche-Posay Substiane Riche Anti-Aging Care 40 ml

https://www.google.com/s2/favicons?domain=skincaredirect.com.au&sz=64skincaredirect.com.au

$71.50

La Roche Posay Substiane [+] Anti-Aging Replenishing Care(Random Packaging) (40ml/1.35oz)

Free delivery between 7–11 Sept

https://www.google.com/s2/favicons?domain=kogan.com&sz=64Kogan.com

$79.87

La Roche Posay Substiane [+] Anti-Aging Replenishing Care 40ml/1.35oz

14-day returns

https://www.google.com/s2/favicons?domain=medcart.com.au&sz=64Medcart

$81.54

La Roche Posay Substiane [+] Anti-Aging Replenishing Care 40ml/1.35oz

Free delivery between 3–10 Sept

https://www.google.com/s2/favicons?domain=medcart.com.au&sz=64Medcart

$81.54

La Roche Posay Substiane [+] Anti-Aging Replenishing Care (Unboxed) 40ml/1.35oz

Free delivery between 3–10 Sept

https://www.google.com/s2/favicons?domain=harveynorman.com.au&sz=64Harvey Norman

$86.00

La Roche Posay Substiane [+] Anti-Aging Replenishing Care - 40ml / 1.35oz

Delivery $9

Price history

Price history

Please note: price history and price alerts are not available for some stores, including Amazon.com.au.

Reviews

8 January 2021paula .l

originally posted on influenster.com

Received this complimentary from Influenster Vox Box .,,. I’m three weeks into this product, I use it in the morning and before bed. I haven’t seen any dramatic changes in my skin. It’s a decent moisturizer, though I’m not sure I would run out and purchase it again. It’s a little pricey, not that I mind spending the money if I absolutely loved it, but I don’t so I don’t foresee me purchasing it again. I will give it an honest trial and finish out the tube and if by some miracle I begin to see or feel a change That might change my mind for a future purchase. A few things to point out, it doesn’t have fragrance, so it’s scent free. It has not given me any negative side effects, It doesn’t absorb into my skin, I need to RUB it in, I usually dab a few dots on my face ... MoreReceived this complimentary from Influenster Vox Box .,,. I’m three weeks into this product, I use it in the morning and before bed. I haven’t seen any dramatic changes in my skin. It’s a decent moisturizer, though I’m not sure I would run out and purchase it again. It’s a little pricey, not that I mind spending the money if I absolutely loved it, but I don’t so I don’t foresee me purchasing it again. I will give it an honest trial and finish out the tube and if by some miracle I begin to see or feel a change That might change my mind for a future purchase. A few things to point out, it doesn’t have fragrance, so it’s scent free. It has not given me any negative side effects, It doesn’t absorb into my skin, I need to RUB it in, I usually dab a few dots on my face then have to work it in , you don’t need a lot so I will say that even though it looks like a small-medium tube it does last. One big negative was squeezing it out if the tube.

A Little Goes A LONG Way!
16 June 2023

originally posted on lovelyskin.com

I put a pea size on my finger and warm it up. I use it around my eyes and on my throat. It applies very smoothly and provides a great barrier. I haven’t seen a difference in my skin, but I will most likely purchase it again. I have been impressed with the quality of the product line La Roche-Posay has. If you have dry delicate skin, you should try this product.

Big on moisture. Too small of a tube
2 April 2023Jdpt1984

originally posted on laroche-posay.us

I love this moisturizer. I am 61 and needed a rich emollient cream. My dermatologist recommended laroche posay. I am happy with the product but very unhappy with the size of the tube. Website indicates this product should last 3 months. No way!!! I am using it sparingly. I wish the manufacturer would offer a larger tube size. It is expensive but I find most anti aging high end moisturizers are costly.

Specification

Product dimensions15.5 x 2.8 x 3.5 cm; 60 Kilograms
Country of originUSA
ScentCoconut
Item formCream
Active ingredientsbenzoic acid,soy

Price comparison

Updated about 11 hours ago
Please note: price history and price alerts are not available for some stores, including Amazon.com.au.
https://www.google.com/s2/favicons?domain=freshbeautyco.com.au&sz=64
Fresh Beauty Co.

$38.05

Out of stock

La Roche Posay Substiane Visible Density And Volume Replenishing Care (Exp. Date: 06/2023) 40ml/1.35oz

Delivery between 8–16 Sept $8.95

https://www.google.com/s2/favicons?domain=freshbeautyco.com.au&sz=64
Fresh Beauty Co.

$76.60

Out of stock

La Roche Posay Substiane Visible Density And Volume Replenishing Care 40ml/1.35oz

Delivery between 8–16 Sept $8.95

https://www.google.com/s2/favicons?domain=freshbeautyco.com.au&sz=64
Fresh Beauty Co.

$83.20

Out of stock

La Roche Posay Substiane [+] Anti-Aging Replenishing Care 40ml/1.35oz

Delivery between 7–15 Sept $8.95

https://www.google.com/s2/favicons?domain=skinlovers.com&sz=64
skinlovers.com

$51.48

Out of stock

La Roche-Posay Substiane Cream 40ml

Delivery between 9–11 Sept $10.34

https://www.google.com/s2/favicons?domain=soin-et-nature.com&sz=64
Soin et Nature

$68.93

Out of stock

La Roche-Posay Substiane Riche Anti-Aging Care 40 ml

Price history

Price history

Please note: price history and price alerts are not available for some stores, including Amazon.com.au.

Reviews

8 January 2021

Received this complimentary from Influenster Vox Box .,,. I’m three weeks into this product, I use it in the morning and before bed. I haven’t seen any dramatic changes in my skin. It’s a decent moisturizer, though I’m not sure I would run out and purchase it again. It’s a little pricey, not that I mind spending the money if I absolutely loved it, but I don’t so I don’t foresee me purchasing it again. I will give it an honest trial and finish out the tube and if by some miracle I begin to see or feel a change That might change my mind for a future purchase. A few things to point out, it doesn’t have fragrance, so it’s scent free. It has not given me any negative side effects, It doesn’t absorb into my skin, I need to RUB it in, I usually dab a few dots on my face ... MoreReceived this complimentary from Influenster Vox Box .,,. I’m three weeks into this product, I use it in the morning and before bed. I haven’t seen any dramatic changes in my skin. It’s a decent moisturizer, though I’m not sure I would run out and purchase it again. It’s a little pricey, not that I mind spending the money if I absolutely loved it, but I don’t so I don’t foresee me purchasing it again. I will give it an honest trial and finish out the tube and if by some miracle I begin to see or feel a change That might change my mind for a future purchase. A few things to point out, it doesn’t have fragrance, so it’s scent free. It has not given me any negative side effects, It doesn’t absorb into my skin, I need to RUB it in, I usually dab a few dots on my face then have to work it in , you don’t need a lot so I will say that even though it looks like a small-medium tube it does last. One big negative was squeezing it out if the tube.

paula .l originally posted on influenster.com
A Little Goes A LONG Way!
16 June 2023

I put a pea size on my finger and warm it up. I use it around my eyes and on my throat. It applies very smoothly and provides a great barrier. I haven’t seen a difference in my skin, but I will most likely purchase it again. I have been impressed with the quality of the product line La Roche-Posay has. If you have dry delicate skin, you should try this product.

originally posted on lovelyskin.com
Big on moisture. Too small of a tube
2 April 2023

I love this moisturizer. I am 61 and needed a rich emollient cream. My dermatologist recommended laroche posay. I am happy with the product but very unhappy with the size of the tube. Website indicates this product should last 3 months. No way!!! I am using it sparingly. I wish the manufacturer would offer a larger tube size. It is expensive but I find most anti aging high end moisturizers are costly.

Jdpt1984 originally posted on laroche-posay.us
Great product; poor packaging
5 April 2023

This face cream is nice and I’ve seen results. However it’s horrible packaging and very challenging to get the product out of the tube. I’m starting to run low and I’m guessing I will need to cut open the tube in order to get the last bit out. Perhaps a jar would work better for this particular cream.

TrishTM originally posted on laroche-posay.us
I Love La Roche Posay!
2 December 2022

I absolutely am in love with this product line! My sensitive skin looks and feeling amazing.I have always cared for my skin and always had compliments even when I was younger . Lately i've noticed my face had begun to have less volume in the last year. 10 years ago I started with just 1 product Anthelios sunscreen, then Substaine Eyes, Toleriane demo cleanser & Miscellar water ultra sensitive. Now I am a huge fan of Substiane riche and HyaluB5 . I use Toleriane demo cleanser & Micellar water ultra reactive skin & Hyalu5 every night I thrilled with the results. Thank you La Roche Posay

Bibi girl originally posted on laroche-posay.ca
Just starting out..
12 February 2023

I am just finishing my first tube so I can't give it a true review. Feels good but I don't see any changes yet. I expect to see firming for 'sagging skin.' I'm in my mid 60's & have always been told I look 10 years younger but this sagging skin has just started about 1 year ago. I bought 2 so I can give it a chance to work. Hv used LA Roche-Posay since yr 2000 off & on. I've used Retinol & Vitamin C with great results in the past. I will give another review next month 👍

MareBo originally posted on laroche-posay.us
Need it larger
27 April 2023

I use it daily, and no one can guess my age. And it would get five stars for me if the packaging was larger. From a cost to benefit ratio, as well as for ecological concerns, why is the package so thick and the volume of product so small? We need a 4 ounce version or a 6 ounce version for those of us who use it daily so we don’t keep having to toss it into the recycling bin. And because it’s thick, and I’m older, it’s hard to squeeze out the last of it. So now I cut it open so I can have access to what’s left inside. I can usually get another five days worth of product after cutting the top open. Laroche Posey don’t you care about the environment?

MamaTrauma originally posted on laroche-posay.us
Not hydrating
31 March 2022

I have very dry skin from the winter and have been looking for a cream to rehydrate it. I was really excited to try this but it does not love up to its claims. I've used it morning and night and it doesn't leave my skin hydrated for very long, it even has a strange feeling on my skin. It's also heavily scented which I don't like. I use lots of La Roche items that I like and was hoping this would be my saviour to really dry skin, but it isn't. Unfortunately they don't do free returns either. Would not recommend for someone truly looking to repair dry skin.

JTracey originally posted on laroche-posay.ca
Oily on skin and bad smell after sleeping with it
11 July 2023

I love La Roche products. I purchased this product to add to my anti aging routine. This is the only product I do not like by them. My face was always extremely oily after use and there is a strange smell every time I would wake up in the morning from using this product.For reference I am 37 with combination skin.

LouLou3 originally posted on laroche-posay.us
very light and pleasant moisturizer
6 June 2023

I can always depend on La Roche to be hydrating and non irritating to my sensitive skin. I use a prescription retinoid, which makes my skin quite dry. Many people wrote negative things about this moisturizer based on price and container. As far as price goes, price per ounce is actually less than similar products. The tube is excellent size for a purse or travel instead of a large clunky jar. When it runs out, I usually cut the top off, and use my finger to extract the remaining cream(I do this with toothpaste too!) Warm up the cream on your fingers before applying to make it easier to spread since it's quite thick.

originally posted on lovelyskin.com

Specification

Product dimensions15.5 x 2.8 x 3.5 cm; 60 Kilograms
Country of originUSA
ScentCoconut
Item formCream
Active ingredientsbenzoic acid,soy

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