O'Keeffe's Working Hands Hand Cream is a concentrated hand cream that heals, relieves and repairs extremely dry, cracked hands Creates a protective layer on the skin's surface that instantly boosts moisture levels and helps prevent further moisture loss Makes a difference you will feel within days For best results apply after hand washing, after bathing, and at bedtime, as these are the most effective times for moisturizing extremely dry skin Safe for people with Diabetes This Hand Cream is a concentrated, highly effective moisturizer that relieves extremely dry hands that frequently crack. This odorless, non-greasy formula hydrates the skin a helping it retain moisture and making a difference you feel in days. It is safe for people with diabetes.