Packaging should be the same as what is found in a retail store, unless the item is handmade or was packaged by the manufacturer in non-retail packaging, such as an unprinted box or plastic bag. See the seller's listing for full details.
Packaging should be the same as what is found in a retail store, unless the item is handmade or was packaged by the manufacturer in non-retail packaging, such as an unprinted box or plastic bag. See the seller's listing for full details.
Vitamin D3 50,000 IU
Packaging should be the same as what is found in a retail store, unless the item is handmade or was packaged by the manufacturer in non-retail packaging, such as an unprinted box or plastic bag. See the seller's listing for full details.
Packaging should be the same as what is found in a retail store, unless the item is handmade or was packaged by the manufacturer in non-retail packaging, such as an unprinted box or plastic bag. See the seller's listing for full details.
in 32 offers
The lowest price for Vitamin D3 50,000 IU right now is $15.69 at iHerb, compared across 23 retailers.
The all-time low was $9.99 on 19 Dec 2025 — today's price is 57% above the lowest ever. It has been notably cheaper before — worth setting a price alert.
Prices last updated 8 June 2026.
Last updated at 08/06/2026 15:50:15
Vitamatic, Vitamin D3, 1,250 mcg (50,000 IU), 60 Vegetable Capsules
Delivery $40
Vitamatic Vitamin D3 50,000 IU as Cholecalciferol, Once Weekly Dose, 1250 mcg, 60 Veggie
Delivery between 13–17 June $14.10
Vitamatic Vitamin D3 50,000 IU as Cholecalciferol, Once Weekly Dose, 1250 mcg, 60 Veggie
Delivery between 13–17 June $13.14
Vitamatic Vitamin D3 50,000 IU as Cholecalciferol, Once Weekly Dose, 1250 mcg, 60 Veggie
Delivery between 13–17 June $13.96
Vitamatic 3 Pack Vitamin D3 50,000 IU as Cholecalciferol, Once Weekly Dose, 1250 mcg, 60
Delivery between 13–17 June $13.96
Vitamatic Vitamin D3 50,000 IU as Cholecalciferol, Once Weekly Dose, 1250 mcg, 60 Veggie
Delivery between 13–17 June $8.44
Vitamatic 3 Pack Vitamin D3 50,000 IU as Cholecalciferol, Once Weekly Dose, 1250 mcg, 60
Delivery between 13–17 June $8.44
Vitamatic Vitamin D3 50,000 IU as Cholecalciferol, Once Weekly Dose, 1250 mcg, 60 Veggie
Delivery between 13–17 June $15.40
Vitamatic 3 Pack Vitamin D3 50,000 IU as Cholecalciferol, Once Weekly Dose, 1250 mcg, 60
Delivery between 13–17 June $15.40
Vitamatic, Vitamin D3, 1,250 mcg (50,000 IU), 60 Veggie Capsules
Free delivery between 17–19 June
originally posted on walmart.com
I was told by my doctor that my test results showed that I was low on vitamin D. I was prescribed vitamin D for one month and she told me to start taking vitamin D over the counter after that. I purchased some but they were daily dose and I would find myself forgetting to take them several days out of the week, so that wasn't doing me much good. I saw the Vitamatic vitamin D3 that were a weekly dose so I decided that would be much better because if I happened to forget to take it, I could just take it the following day. I decided that I would take them every Monday morning and so far that seems to work out pretty well, I actually have remembered to take them and haven't missed a dose yet. If I do though, I could take it on Tuesday. I seem to feel better and my ... MoreI was told by my doctor that my test results showed that I was low on vitamin D. I was prescribed vitamin D for one month and she told me to start taking vitamin D over the counter after that. I purchased some but they were daily dose and I would find myself forgetting to take them several days out of the week, so that wasn't doing me much good. I saw the Vitamatic vitamin D3 that were a weekly dose so I decided that would be much better because if I happened to forget to take it, I could just take it the following day. I decided that I would take them every Monday morning and so far that seems to work out pretty well, I actually have remembered to take them and haven't missed a dose yet. If I do though, I could take it on Tuesday. I seem to feel better and my energy level is much better than before. I live in Upper Michigan so we have a lot of days without sunshine, especially in our long winters with cloudy and gloomy days so I see why I am in need of more vitamin D. I would definitely recommend these to anyone who needs more vitamin D and the weekly dose is great!
originally posted on walmart.com
I am not always great with remembering to take my supplements as needed. I often set reminders and count on myself to make a habit of taking them like clockwork. This weekly dose was easy to add in my routine, I take it at the same time every week and not having to keep up with it on a day by basis makes it so much simpler. I like that it keeps my mood and energy up and also helpse to absorb the extra calcium I need. There is no unpleasant aftertaste and it’s super easy to swallow. The best part is that this bottle lasts at least a year. I love when I can get something in bulk and not have to buy it so often and since it’s a weekly dose it’s not taking up an exorbitant amount of room in my medicine cabinet. This is definitely a vitamin I have been lacking in for ... MoreI am not always great with remembering to take my supplements as needed. I often set reminders and count on myself to make a habit of taking them like clockwork. This weekly dose was easy to add in my routine, I take it at the same time every week and not having to keep up with it on a day by basis makes it so much simpler. I like that it keeps my mood and energy up and also helpse to absorb the extra calcium I need. There is no unpleasant aftertaste and it’s super easy to swallow. The best part is that this bottle lasts at least a year. I love when I can get something in bulk and not have to buy it so often and since it’s a weekly dose it’s not taking up an exorbitant amount of room in my medicine cabinet. This is definitely a vitamin I have been lacking in for some time now and I wanted to add it into my refining but it’s hard to get your levels right when you are struggling to take it every day. I never have to worry about it with this type. It seems to absorb very well and I’m looking forward to my next bloodwork draw to see if it’s helping to keep me on track. I just wish all of my vitamins could be taken as weekly doses, it would certainly make keeping up with them a lot easier.
originally posted on ebay.com
I purchased these Vitamin D pills a couple of months ago because my Vitamin D levels have been awful now for a few years due to some ongoing health issues. I had tried many vitamins from other companies and they did nothing, including those sent out by the VA as part of our prescription coverage. In the first 20 or so days, I had my Vitamin D levels near the higher side of recommendations where before I was getting abysmal readings. This change also seems to have helped other overall immune health markers also because they have gone up also and the only change was this brand of Vitamin D. My doctor has warned me that I might not want to take them so often due to the fact that too much vitamin D can also be bad, but now that my numbers are in the healthy range I just ... MoreI purchased these Vitamin D pills a couple of months ago because my Vitamin D levels have been awful now for a few years due to some ongoing health issues. I had tried many vitamins from other companies and they did nothing, including those sent out by the VA as part of our prescription coverage. In the first 20 or so days, I had my Vitamin D levels near the higher side of recommendations where before I was getting abysmal readings. This change also seems to have helped other overall immune health markers also because they have gone up also and the only change was this brand of Vitamin D. My doctor has warned me that I might not want to take them so often due to the fact that too much vitamin D can also be bad, but now that my numbers are in the healthy range I just need to experiment more with what actually is healthy for me. Great product, although I wish they would put them in containers with more pills because this 60 pills to a bottle is for the birds. The only thing they are doing is finding a way to gouge us more, while forcing the use of additional plastic bottles and ththtincreased shipping costs. If you are providing a product for health, then you should also be concerned with the world health and that is a lot of extra plastic bottles to be recycled plus the additional carbon required for shipping.
Vitamatic, Vitamin D3, 1,250 mcg (50,000 IU), 60 Vegetable Capsules
Delivery $40
Vitamatic Vitamin D3 50,000 IU as Cholecalciferol, Once Weekly Dose, 1250 mcg, 60 Veggie
Delivery between 13–17 June $14.10
Vitamatic Vitamin D3 50,000 IU as Cholecalciferol, Once Weekly Dose, 1250 mcg, 60 Veggie
Delivery between 13–17 June $13.14
Vitamatic Vitamin D3 50,000 IU as Cholecalciferol, Once Weekly Dose, 1250 mcg, 60 Veggie
Delivery between 13–17 June $13.96
Vitamatic 3 Pack Vitamin D3 50,000 IU as Cholecalciferol, Once Weekly Dose, 1250 mcg, 60
Delivery between 13–17 June $13.96
I was told by my doctor that my test results showed that I was low on vitamin D. I was prescribed vitamin D for one month and she told me to start taking vitamin D over the counter after that. I purchased some but they were daily dose and I would find myself forgetting to take them several days out of the week, so that wasn't doing me much good. I saw the Vitamatic vitamin D3 that were a weekly dose so I decided that would be much better because if I happened to forget to take it, I could just take it the following day. I decided that I would take them every Monday morning and so far that seems to work out pretty well, I actually have remembered to take them and haven't missed a dose yet. If I do though, I could take it on Tuesday. I seem to feel better and my ... MoreI was told by my doctor that my test results showed that I was low on vitamin D. I was prescribed vitamin D for one month and she told me to start taking vitamin D over the counter after that. I purchased some but they were daily dose and I would find myself forgetting to take them several days out of the week, so that wasn't doing me much good. I saw the Vitamatic vitamin D3 that were a weekly dose so I decided that would be much better because if I happened to forget to take it, I could just take it the following day. I decided that I would take them every Monday morning and so far that seems to work out pretty well, I actually have remembered to take them and haven't missed a dose yet. If I do though, I could take it on Tuesday. I seem to feel better and my energy level is much better than before. I live in Upper Michigan so we have a lot of days without sunshine, especially in our long winters with cloudy and gloomy days so I see why I am in need of more vitamin D. I would definitely recommend these to anyone who needs more vitamin D and the weekly dose is great!
I am not always great with remembering to take my supplements as needed. I often set reminders and count on myself to make a habit of taking them like clockwork. This weekly dose was easy to add in my routine, I take it at the same time every week and not having to keep up with it on a day by basis makes it so much simpler. I like that it keeps my mood and energy up and also helpse to absorb the extra calcium I need. There is no unpleasant aftertaste and it’s super easy to swallow. The best part is that this bottle lasts at least a year. I love when I can get something in bulk and not have to buy it so often and since it’s a weekly dose it’s not taking up an exorbitant amount of room in my medicine cabinet. This is definitely a vitamin I have been lacking in for ... MoreI am not always great with remembering to take my supplements as needed. I often set reminders and count on myself to make a habit of taking them like clockwork. This weekly dose was easy to add in my routine, I take it at the same time every week and not having to keep up with it on a day by basis makes it so much simpler. I like that it keeps my mood and energy up and also helpse to absorb the extra calcium I need. There is no unpleasant aftertaste and it’s super easy to swallow. The best part is that this bottle lasts at least a year. I love when I can get something in bulk and not have to buy it so often and since it’s a weekly dose it’s not taking up an exorbitant amount of room in my medicine cabinet. This is definitely a vitamin I have been lacking in for some time now and I wanted to add it into my refining but it’s hard to get your levels right when you are struggling to take it every day. I never have to worry about it with this type. It seems to absorb very well and I’m looking forward to my next bloodwork draw to see if it’s helping to keep me on track. I just wish all of my vitamins could be taken as weekly doses, it would certainly make keeping up with them a lot easier.
I purchased these Vitamin D pills a couple of months ago because my Vitamin D levels have been awful now for a few years due to some ongoing health issues. I had tried many vitamins from other companies and they did nothing, including those sent out by the VA as part of our prescription coverage. In the first 20 or so days, I had my Vitamin D levels near the higher side of recommendations where before I was getting abysmal readings. This change also seems to have helped other overall immune health markers also because they have gone up also and the only change was this brand of Vitamin D. My doctor has warned me that I might not want to take them so often due to the fact that too much vitamin D can also be bad, but now that my numbers are in the healthy range I just ... MoreI purchased these Vitamin D pills a couple of months ago because my Vitamin D levels have been awful now for a few years due to some ongoing health issues. I had tried many vitamins from other companies and they did nothing, including those sent out by the VA as part of our prescription coverage. In the first 20 or so days, I had my Vitamin D levels near the higher side of recommendations where before I was getting abysmal readings. This change also seems to have helped other overall immune health markers also because they have gone up also and the only change was this brand of Vitamin D. My doctor has warned me that I might not want to take them so often due to the fact that too much vitamin D can also be bad, but now that my numbers are in the healthy range I just need to experiment more with what actually is healthy for me. Great product, although I wish they would put them in containers with more pills because this 60 pills to a bottle is for the birds. The only thing they are doing is finding a way to gouge us more, while forcing the use of additional plastic bottles and ththtincreased shipping costs. If you are providing a product for health, then you should also be concerned with the world health and that is a lot of extra plastic bottles to be recycled plus the additional carbon required for shipping.
I did my research on Vitamin D supplements before trying this product and I think it is important to note that there is a difference between Vitamin D2 and Vitamin D3. D3 is known as the sunshine vitamin, it is what is produced in our bodies when exposed to sunshine but since we are very conscious of sun exposure and typically wear sunscreen, most of us are lacking the proper amounts of this vitamin in our bodies. This is the perfect vitamin to take to compensate. Taking D3 will lead to more absorption and create higher stores of the vitamin in your body. It aids in the absorption of calcium and helps to prevent osteoporosis, which as a woman who has had a child, this is a concern for me. I am constantly looking for a good vitamin to help maintain Vitamin D in my ... MoreI did my research on Vitamin D supplements before trying this product and I think it is important to note that there is a difference between Vitamin D2 and Vitamin D3. D3 is known as the sunshine vitamin, it is what is produced in our bodies when exposed to sunshine but since we are very conscious of sun exposure and typically wear sunscreen, most of us are lacking the proper amounts of this vitamin in our bodies. This is the perfect vitamin to take to compensate. Taking D3 will lead to more absorption and create higher stores of the vitamin in your body. It aids in the absorption of calcium and helps to prevent osteoporosis, which as a woman who has had a child, this is a concern for me. I am constantly looking for a good vitamin to help maintain Vitamin D in my body and I have found it!Vitamatic Vitamin D3 is meant to be taken once a week and helps promote a healthy immune system while also strengthening bones and teeth. As someone who is not a big milk person, I definitely was excited to get this vitamin! This bottle came with 60 capsules which equates out to over a year of vitamins. I recommend taking the vitamin with food, as does the bottle. It is too early to tell overall if there has been a change in my body as far as absorption of the vitamin as I have only been taking it for two weeks but I have noticed a slight change in my energy level. I am a single mom who works 60 hours a week minimum so I am constantly tired. I have noticed that I am not as fatigued as usual and I hope that with continued use over time, my energy level will continue to rise.I really like that the vitamin came as a veggie capsule. I am not one for powdery pills because the second they hit your mouth, they start to melt and you get that powdery taste, it makes me gag. Thankfully with this vitamin, it is a veggie gel capsule that goes down easily with whatever drink you choose to take it with. I use water typically, sometimes juice. There was no after taste and it was easy to swallow. All in all, I am thrilled with this vitamin and can’t wait to see how it continues to help my body overall! Thank you, Vitamatic for producing something a picky vitamin user can take and actually enjoy using!
I had a physical a little over six months ago. Thankfully everything with me is well but my doctor did let me know that my blood work showed that I was deficient in vitamin D. He recommended that I start taking a vitamin D supplement right away. He said it was absolutely critical for multiple functions like immune health, bone strength, kidney function and even help regulate my mood.As we spend so much more time indoors these days, I think it’s critical for us to not overlook our vitamin D intake. I’ve tried a few different brands but this one is my favorite so far. What I really like about this particular brand is that you only need to take one of these vitamin supplements a week. Each pill contains 50,000 IU of vitamin D so 4 times a month and you are good to ... MoreI had a physical a little over six months ago. Thankfully everything with me is well but my doctor did let me know that my blood work showed that I was deficient in vitamin D. He recommended that I start taking a vitamin D supplement right away. He said it was absolutely critical for multiple functions like immune health, bone strength, kidney function and even help regulate my mood.As we spend so much more time indoors these days, I think it’s critical for us to not overlook our vitamin D intake. I’ve tried a few different brands but this one is my favorite so far. What I really like about this particular brand is that you only need to take one of these vitamin supplements a week. Each pill contains 50,000 IU of vitamin D so 4 times a month and you are good to go. The pills are tasteless, not very large and are easy to swallow. 60 pills come in the container so they will last you awhile. The veggie capsule has no taste so you can take it with just water and won’t be let with an off-putting aftertaste. Really happy overall and would recommend you give them a try.
These new Vitamatic Vitamin D3 supplements look just like any other Vitamin D3 supplement in easy to-swallow pill form -- the major difference being that they are formulated to deliver a WEEK'S worth of Vitamin D supplementation, and thus, are to be taken on a weekly (as opposed to DAILY) basis. Because they pack a whopping 50,000 IU of vitamin D3 cholecalciferol, you should in fact NOT take them for DAILY use! This one package contains 60 capsules -- so essentially, over a YEAR'S worth of Vitamin D3!Although my vitamin D needs are generally met through sun exposure, I have acquired these for my older mother who spends a much greater deal of time indoors, needs to optimize her bone health, and can easily forget to take tablets on a daily basis. And moving into the ... MoreThese new Vitamatic Vitamin D3 supplements look just like any other Vitamin D3 supplement in easy to-swallow pill form -- the major difference being that they are formulated to deliver a WEEK'S worth of Vitamin D supplementation, and thus, are to be taken on a weekly (as opposed to DAILY) basis. Because they pack a whopping 50,000 IU of vitamin D3 cholecalciferol, you should in fact NOT take them for DAILY use! This one package contains 60 capsules -- so essentially, over a YEAR'S worth of Vitamin D3!Although my vitamin D needs are generally met through sun exposure, I have acquired these for my older mother who spends a much greater deal of time indoors, needs to optimize her bone health, and can easily forget to take tablets on a daily basis. And moving into the winter months, it is important that both of us can maintain adequate Vitamin D3 levels as sun exposure decreases and we must keep out immune systems functioning at an optimal level.The bills themselves are of your typical cellulose coated, double-sided construction, and 3/4 inch long. They are free of allergens including sugar, starch, sodium, yeast, soy, corn, wheat, egg, artificial colors, flavors, or preservatives. They are suitable for vegan use.Although I see no USP certification on the pill bottle itself (this is the "gold standard" for assuring quality of dietary supplements), there is a NON-GMO certification on the bottle (if that is of concern to you), and a GMP certification (this does not certify efficacy but does certify manufacturing quality control practices have been adhered to in accordance with intended use of the product.) Additionally, this product has been manufactured in the USA.Packaging wise, I do appreciate that the bottle itself is only 3 3/4 inches tall -- far more compact that many pill bottles containing an equal amount of product!Unfortunately at the time of review, I cannot tell you whether the pills have actually maintained optimal vitamin D3 levels as that would require several months of continuous use a blood draw from a physician to determine.
My husband was told to take Vitamin D3 by his doctor. He is really bad about taking his pills and I have tried everything to remind him and get him to take his daily medications. When I saw this product, I was really happy that it's once a week! I did check with his doctor to make sure that this was okay for him and his doctor said it would be fine.This bottle contains 60 pills that are to be taken once a week so this entire bottle will last a year. The size of the capsules are a normal size, and easy enough to swallow.My husband has been taking Vitamin D3 since he had a bone spur removed and the surgery was intensive. The doctor had him take this to help with revery and then to contain taking it to strengthen his bones. I like that it promotes a healthy immune ... MoreMy husband was told to take Vitamin D3 by his doctor. He is really bad about taking his pills and I have tried everything to remind him and get him to take his daily medications. When I saw this product, I was really happy that it's once a week! I did check with his doctor to make sure that this was okay for him and his doctor said it would be fine.This bottle contains 60 pills that are to be taken once a week so this entire bottle will last a year. The size of the capsules are a normal size, and easy enough to swallow.My husband has been taking Vitamin D3 since he had a bone spur removed and the surgery was intensive. The doctor had him take this to help with revery and then to contain taking it to strengthen his bones. I like that it promotes a healthy immune system. We work with the public and any measures that help us to prevent illness is appreciated.
Vitamatic Once Weekly Vitamin D3 50,000 IU is a once weekly dose of Vitamin D3. I would suggest consulting a health-care provider before beginning this, or really any, vitamin supplement, as it is a higher dose than usual.This particular supplement is very convenient since it only has to be taken once a week. Given the current pandemic, Vitamin D3 is suggested by many doctors to be taken in conjunction with Vitamin C. I know I’ve been advised by my health care provider to take it in conjunction with Vitamin C and Zinc as an immune booster. As an educator who could possibly be having to teach from the classroom in the not so distant future, it is imperative that I do what is necessary to boost my immune system so as I can try my best to prevent from getting ... MoreVitamatic Once Weekly Vitamin D3 50,000 IU is a once weekly dose of Vitamin D3. I would suggest consulting a health-care provider before beginning this, or really any, vitamin supplement, as it is a higher dose than usual.This particular supplement is very convenient since it only has to be taken once a week. Given the current pandemic, Vitamin D3 is suggested by many doctors to be taken in conjunction with Vitamin C. I know I’ve been advised by my health care provider to take it in conjunction with Vitamin C and Zinc as an immune booster. As an educator who could possibly be having to teach from the classroom in the not so distant future, it is imperative that I do what is necessary to boost my immune system so as I can try my best to prevent from getting sick.The benefit of this is one less pill to take on a daily basis. I have felt no noticeable side-effects as I transitioned from the daily dose to a weekly dose. I did stop taking my regular vitamin D3 a week before I began this one, just to be on the safe side. All in all, I would recommend this product for anyone who finds it tedious to take a supplement on a weekly basis or who needs a boost of Vitamin D3 in their system.
I received this supplement for my spouse as she takes a daily dosage of D3. The packaging is secure with a common plastic bottle, sealed with a heat seal plastic seal and a factory sealed bottle opening underneath the cap. The label on the bottle has very good information, which you do need to read and pay attention to. The white capsules are big, about the size of a normal 1000mg type capsule. This is supposed to be a once a week dosage, 50,000 IU, 1250mcg. Check with your physician, ours said this was to high for the application that is needed. Research shows this dosage spikes high then goes down daily. It doesn’t provide a maintenance level and the instructions state NOT for long term use. Though we will not be using these capsules the overall safe packaging and ... MoreI received this supplement for my spouse as she takes a daily dosage of D3. The packaging is secure with a common plastic bottle, sealed with a heat seal plastic seal and a factory sealed bottle opening underneath the cap. The label on the bottle has very good information, which you do need to read and pay attention to. The white capsules are big, about the size of a normal 1000mg type capsule. This is supposed to be a once a week dosage, 50,000 IU, 1250mcg. Check with your physician, ours said this was to high for the application that is needed. Research shows this dosage spikes high then goes down daily. It doesn’t provide a maintenance level and the instructions state NOT for long term use. Though we will not be using these capsules the overall safe packaging and well written instructions seems to say that VITAMATIC packaging shows customer care.
I was already prescribed a daily dose of 2000 IU, don't get a lot of sun and don't always eat right. Because I already had low levels of Vitamin D3, I was given the go-ahead by my doctor.50,000 IU Vitamin D3 is a lot for the average person. I suggest you should contact your doctor first.Here is some more information from the Mayo Clinic:OverviewVitamin D is necessary for building and maintaining healthy bones. That's because calcium, the primary component of bone, can only be absorbed by your body when vitamin D is present. Your body makes vitamin D when direct sunlight converts a chemical in your skin into an active form of the vitamin (calciferol).Vitamin D isn't found in many foods, but you can get it from fortified milk, fortified cereal, and fatty ... MoreI was already prescribed a daily dose of 2000 IU, don't get a lot of sun and don't always eat right. Because I already had low levels of Vitamin D3, I was given the go-ahead by my doctor.50,000 IU Vitamin D3 is a lot for the average person. I suggest you should contact your doctor first.Here is some more information from the Mayo Clinic:OverviewVitamin D is necessary for building and maintaining healthy bones. That's because calcium, the primary component of bone, can only be absorbed by your body when vitamin D is present. Your body makes vitamin D when direct sunlight converts a chemical in your skin into an active form of the vitamin (calciferol).Vitamin D isn't found in many foods, but you can get it from fortified milk, fortified cereal, and fatty fish such as salmon, mackerel and sardines.The amount of vitamin D your skin makes depends on many factors, including the time of day, season, latitude and your skin pigmentation. Depending on where you live and your lifestyle, vitamin D production might decrease or be completely absent during the winter months. Sunscreen, while important, also can decrease vitamin D production.Many older adults don't get regular exposure to sunlight and have trouble absorbing vitamin D, so taking a multivitamin with vitamin D will likely help improve bone health. The recommended daily amount of vitamin D is 400 international units (IU) for children up to age 12 months, 600 IU for ages 1 to 70 years, and 800 IU for people over 70 years.EvidenceResearch on vitamin D use for specific conditions shows:Cancer. Research suggests that vitamin D, especially when taken with calcium, might help prevent certain cancers.Cognitive health. Early research suggests that vitamin D might play a role in cognitive health. In one small study of adults age 60 years and older being treated for dementia, researchers found that taking a vitamin D supplement helped improve cognitive function.Inherited disorders. Vitamin D supplements can be used to help treat inherited disorders resulting from an inability to absorb or process vitamin D, such as familial hypophosphatemia.Multiple sclerosis. Research suggests that long-term vitamin D supplementation reduces the risk of multiple sclerosis.Osteomalacia. Vitamin D supplements are used to treat adults with severe vitamin D deficiency, resulting in loss of bone mineral content, bone pain, muscle weakness and soft bones (osteomalacia).Osteoporosis. Studies suggest that people who get enough vitamin D and calcium in their diets can slow bone mineral loss, help prevent osteoporosis and reduce bone fractures.Psoriasis. Applying vitamin D or a topical preparation that contains a vitamin D compound called calcipotriene to the skin can treat plaque-type psoriasis in some people.Rickets. This rare condition develops in children with vitamin D deficiency. Supplementing with vitamin D can prevent and treat the problem.Our takeGreen light: Generally safeGenerally safeWithout vitamin D your bones can become soft, thin and brittle. Insufficient vitamin D is also connected to osteoporosis and some types of cancer. If you don't get enough vitamin D through sunlight or dietary sources, you might need vitamin D supplements.Safety and side effectsTaken in appropriate doses, vitamin D is generally considered safe.However, taking too much vitamin D can be harmful. Children age 9 years and older, adults, and pregnant and breast-feeding women who take more than 4,000 IU a day of vitamin D might experience:NauseaVomitingPoor appetiteConstipationWeaknessWeight lossConfusionDisorientationHeart rhythm problemsKidney damageInteractionsPossible interactions include:Aluminum. Taking vitamin D and aluminum-containing phosphate binders long term might cause harmful levels of aluminum in people with kidney failure.Anticonvulsants. The anticonvulsants phenobarbital and phenytoin (Dilantin, Phenytek) increase the breakdown of vitamin D and reduce calcium absorption.Atorvastatin (Lipitor). Taking vitamin D might affect the way your body processes this cholesterol drug.Calcipotriene (Dovonex). Don't take vitamin D with this psoriasis drug. The combination might increase the risk of too much calcium in the blood (hypercalcemia).Cholestyramine (Prevalite). Taking this weight-loss drug can reduce your absorption of vitamin D.Cytochrome P450 3A4 (CYP3A4) substrates. Use vitamin D cautiously if you're taking drugs processed by these enzymes.Digoxin (Lanoxin). Avoid taking high doses of vitamin D with this heart medication. High doses of vitamin D can cause hypercalcemia, which increases the risk of fatal heart problems with digoxin.Diltiazem (Cardizem, Tiazac). Avoid taking high doses of vitamin D with this blood pressure drug. High doses of vitamin D can cause hypercalcemia, which might reduce the drug's effectiveness.Orlistat (Xenical, Alli). Taking this weight-loss drug can reduce your absorption of vitamin D.Thiazide diuretics. These blood pressure drugs might decrease urinary calcium excretion. This could lead to hypercalcemia if you are taking vitamin D.Steroids. Taking steroid mediations such as prednisone can reduce calcium absorption and impair your body's processing of vitamin D.Stimulant laxatives. Long-term use of high doses of stimulant laxatives can reduce vitamin D and calcium absorption.Verapamil (Verelan, Calan). Avoid taking high doses of vitamin D with this blood pressure drug. High doses of vitamin D can cause hypercalcemia, which might reduce the drug's effectiveness.
