Fast-acting API GENERAL mediate Freshwater and Saltwater Fish Powder Medication treats a wide variety of parasites in fish, including velvet, fish lice, hole-in-the-head disease (Hexamita spp. & Spironucleus), gill & skin flukes (Dactylogyrus & Gyrodactylus ). For use in fresh and saltwater aquariums. This medication will not color the aquarium water. Dose according to directions on product label and use accordingly.With API Aquarium products, its easy to keep a beautiful saltwater, freshwater or reef aquarium. For over 50 years, API has been creating innovative, research-driven solutions that make it easier to care for your fish and aquarium. API Aquarium Treatment Supplies are designed to work in conjunction with each other to provide best results to control algae, promote healthy bacterial growth and help control and mediate fish diseases and conditions such as ich and fin rot. They work to provide a safe, hospitable environment for fish such as tropical community fish, cichlids, goldfish and more. With API, you can spend more time admiring your fish, and less time scrubbing your tank. Make sure to use all products as directed in order to ensure the best results.