For the treatment of acne When applied to the skin, benzoyl peroxide works by reducing the amount of acne-causing bacteria and by causing the skin to dry and peel. Benzoyl peroxide topical wash 5 percent by Harris Pharmaceuticals Benzoyl peroxide topical wash 5 percent by Harris Pharmaceuticals This medication is used to treat mild to moderate acne. It may be used in combination with other acne treatments. When applied to the skin, benzoyl peroxide works by reducing the amount of acne-causing bacteria and by causing the skin to dry and peel.