SAMe 200 mg 60 Tabs - SAMe from Natural Factors is a joint and mood support supplement. Research suggests that SAMe elevates mood and has a positive effect on behavior. It also maintains cartilage health and contributes to the production of joint supporting compounds. Natural Factors SAMe is enteric coated for maximum bioavailability. Contains no artificial preservatives, color, sweeteners, corn, dairy, soy, starch, wheat or yeast.
SAMe 200 mg 60 Tabs - SAMe from Natural Factors is a joint and mood support supplement. Research suggests that SAMe elevates mood and has a positive effect on behavior. It also maintains cartilage health and contributes to the production of joint supporting compounds. Natural Factors SAMe is enteric coated for maximum bioavailability. Contains no artificial preservatives, color, sweeteners, corn, dairy, soy, starch, wheat or yeast.
in 3 offers
The lowest price for Natural Factors Same 200 MG 30 Slow Release Tablets right now is $32.46 at Win in Health, compared across 3 retailers.
The all-time low was $18.87 on 5 Jan 2026 — today's price is 72% above the lowest ever. It has been notably cheaper before — worth setting a price alert.
Prices last updated 4 July 2026.
Natural Factors Same 200 MG 30 Slow Release Tablets
SAMe 200 mg 60 Tabs - SAMe from Natural Factors is a joint and mood support supplement. Research suggests that SAMe elevates mood and has a positive effect on behavior. It also maintains cartilage health and contributes to the production of joint supporting compounds. Natural Factors SAMe is enteric coated for maximum bioavailability. Contains no artificial preservatives, color, sweeteners, corn, dairy, soy, starch, wheat or yeast.
SAMe 200 mg 60 Tabs - SAMe from Natural Factors is a joint and mood support supplement. Research suggests that SAMe elevates mood and has a positive effect on behavior. It also maintains cartilage health and contributes to the production of joint supporting compounds. Natural Factors SAMe is enteric coated for maximum bioavailability. Contains no artificial preservatives, color, sweeteners, corn, dairy, soy, starch, wheat or yeast.
Last updated at 04/07/2026 16:20:46
Natural Factors SAM-e, 200 mg, 30 Tabs
Affiliate Disclosure: We may receive a small commission for purchases made through this link at no extra cost to you. This helps support our site. Thank you!
SAMe 200 mg iso active 30 Capsules
Delivery $30.65
Natural Factors SAMe 200 mg 30 Slow Release Tablets
Delivery between 6–17 July $28.88
originally posted on iherb.com
I was prescribed Zoloft for lack of motivation/energy due to perimenopause. After reading about the side effects, I got a bit scared so I looked for natural alternatives and found this. (please note that I am *NOT* recommending everyone who is on Zoloft switch to this - just sharing my personal opinion/experience, which might not reflect your situation.)I have been taking it for about a month now and haven't had the bad "dip" in my mental wellbeing. I use a pill cutter to cut in half and take it every morning. I am thinking maybe I can even take alternative days.It's not something that makes me feel "happy" but it definitely helps stabilize my mood.Easy to swallow especially when cut in half.
originally posted on iherb.com
Fantastic product!! I live with Bipolar and PTSD, SAMe has helped to find a good balance with my moods and anxieties. It also has the added benefits of reducing the pains of osteoarthritis. I love it!! My attention to stressful situations is greatly reduced and I a able to focus properly on what's important in my days.
originally posted on iherb.com
I noticed more clean energy within 2 days. I'm 6 weeks in and still feel amazing. Mood is elevated and I'M DREAMING AGAIN. I have autoimmune disorders as well as PTSD, including chronic fatigue for the last 20 years. I have read and tried over 100 different remedies. This is honestly a life saver for me. I hope it can be for anyone else suffering as I did.
| General | |
| Units in Package | 30 |
| Directions | Suggested Usage: 1 tablet on an empty stomach, 2 times per day for 3 weeks; then 1 tablet per day thereafter, or as directed by a health professional. For freshness, store in a cool, dry place. For optimum freshness, refrigerate after opening. |
| Ingredients | Other Ingredients: Microcrystalline Cellulose, Mannitol, Enteric Coating (Methacrylic Acid Copolymer, Triethyl Citrate, Glyceryl Palmitostearate, Silica, Titanium Dioxide, Medium Chain Triglycerides, Yellow Iron Oxide), Glyceryl Behenate, Magnesium Stearate (Vegetable Grade), Silica, Sodium Starch Glycolate). |
| Warnings | Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding or trying to conceive, or if you are taking medication, have a medical condition or anticipate a surgery. Keep out of the reach of children. Sealed for your protection. Do not use if seal is broken. |
Natural Factors SAM-e, 200 mg, 30 Tabs
Affiliate Disclosure: We may receive a small commission for purchases made through this link at no extra cost to you. This helps support our site. Thank you!
SAMe 200 mg iso active 30 Capsules
Delivery $30.65
Natural Factors SAMe 200 mg 30 Slow Release Tablets
Delivery between 6–17 July $28.88
I was prescribed Zoloft for lack of motivation/energy due to perimenopause. After reading about the side effects, I got a bit scared so I looked for natural alternatives and found this. (please note that I am *NOT* recommending everyone who is on Zoloft switch to this - just sharing my personal opinion/experience, which might not reflect your situation.)I have been taking it for about a month now and haven't had the bad "dip" in my mental wellbeing. I use a pill cutter to cut in half and take it every morning. I am thinking maybe I can even take alternative days.It's not something that makes me feel "happy" but it definitely helps stabilize my mood.Easy to swallow especially when cut in half.
Fantastic product!! I live with Bipolar and PTSD, SAMe has helped to find a good balance with my moods and anxieties. It also has the added benefits of reducing the pains of osteoarthritis. I love it!! My attention to stressful situations is greatly reduced and I a able to focus properly on what's important in my days.
I noticed more clean energy within 2 days. I'm 6 weeks in and still feel amazing. Mood is elevated and I'M DREAMING AGAIN. I have autoimmune disorders as well as PTSD, including chronic fatigue for the last 20 years. I have read and tried over 100 different remedies. This is honestly a life saver for me. I hope it can be for anyone else suffering as I did.
Notable good quality for price. No noticable gastro intestinal side effects, as i have experienced with some brands. Good for mood and attention, and mild anti inflamatory. A good buy.
When the pandemic hit we were unable to get our dogs liver supplement, Zentonil. Worldwide supply issues. After doing some research I discovered that Same & Milk Thistle was the same thing. This brand was recommended by Dr. Jones, a holistic vet from the YouTube channel "Veterinary Secrets". Our dog's liver values actually improved on this Same supplement. Better results than the Zentonil & half the price!! Its awesome for dog's liver & cognitive function as well!!
Works better than Zentonil for dogs liver values. One tablet a day on an empty stomach along with a Milk Thistle & Dandelion Root tinctures is amazing. Great price here on iHerb!!!
The quality was excellent packaging was v good. Its benefit was average may be an increase in dosage will work much better there was no bad taste after taking depression was relieved to some extent
SAMe is a very powerful and effective supplement for moods (anxiety, depression, stress). This is a serious supplement and you should talk to a health care provider if you intend on taking it for long term (ie: 6 months or more). It is normally very expensive in Canada, so this is a bargain price! Note: SAMe can raise homocysteine levels (which is not good for the heart) if taken at high does for a long duration. However, this can be offset by taking a Vitamin B complex daily which lowers homocysteine level.
| General | |
| Units in Package | 30 |
| Directions | Suggested Usage: 1 tablet on an empty stomach, 2 times per day for 3 weeks; then 1 tablet per day thereafter, or as directed by a health professional. For freshness, store in a cool, dry place. For optimum freshness, refrigerate after opening. |
| Ingredients | Other Ingredients: Microcrystalline Cellulose, Mannitol, Enteric Coating (Methacrylic Acid Copolymer, Triethyl Citrate, Glyceryl Palmitostearate, Silica, Titanium Dioxide, Medium Chain Triglycerides, Yellow Iron Oxide), Glyceryl Behenate, Magnesium Stearate (Vegetable Grade), Silica, Sodium Starch Glycolate). |
| Warnings | Cautions: As with any supplement, consult your health professional before use if you are pregnant, breastfeeding or trying to conceive, or if you are taking medication, have a medical condition or anticipate a surgery. Keep out of the reach of children. Sealed for your protection. Do not use if seal is broken. |