Thick, rich formula stays in place to help provide relief to your babys diaper rash after just one application The PENATEN brand has been trusted for over 100 years. In addition to the treatment of diaper rash, PENATEN Medicated Cream with 18% active zinc oxide ingredient can be used for the relief of itching due to eczema, minor burns and scalds. How to Use: PENATEN Medicated Cream is best used at the first signs of redness, as it starts working right away. First, wipe the area gently but thoroughly, then pat the area dry " let it dry naturally, if possible. Apply a layer of PENATEN Medicated Cream and fasten a clean diaper, ensuring its not overly tight. By applying a medicated barrier cream at every diaper change, you help treat diaper rash while protecting the skin from further irritation.