All the Potency. None of the Irritation.Silky, fast-absorbing layering serum combines Retinol and patented NIA-114 to fight major signs of aging. Supercharges any skincare routine without the irritating side effects. NIA-114 + Retinol = Faster, smarter anti-aging Our most potent level of Retinol in a silky serum delivers two powerful anti-aging actives in one powerhouse treatment. For Retinol to achieve its age-fighting efficacy, it needs to convert to its active form. The proprietary NIA-114 molecule activates Retinol and strengthens the skin barrier, reducing the sensitivity common to Retinol.The pair forms a dynamic duo to work harder, faster, and more efficiently to deliver superior age-fighting benefits that address all signs of aging, reduce deep-set wrinkles and even out skin tone. Clinically proven to leave skin dramatically more refined and radiant, reducing the appearance of fine lines and smoothing texture for a reduction in the look of pores.