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Last updated at 08/06/2026 06:22:52

Please note: price history and price alerts are not available for some stores, including Amazon.com.au.
Amazon.com.au

$93.95

Thorne Research - Active 5-MTHF 5 mg Folate Vitamin B9-60 Capsules

Delivery $9.99

Affiliate Disclosure: We may receive a small commission for purchases made through this link at no extra cost to you. This helps support our site. Thank you!

eBay.com.au

$93.95

Thorne Active 5-MTHF 5 mg Folate Vitamin B9 - 60 Capsules

Affiliate Disclosure: We may receive a small commission for purchases made through this link at no extra cost to you. This helps support our site. Thank you!

iHerb

$98.51

Thorne, 5-MTHF, 5 mg, 60 Capsules

Free delivery

Price history

Price history

Please note: price history and price alerts are not available for some stores, including Amazon.com.au.

Reviews

Excellent!
4 February 2023iHerb Customer

originally posted on iherb.com

Really like this creatine. I've had others that were very sour and difficult to drink, but not this one! Has no flavor so I am able to mix it with protien shakes or even juice. I also didn't experience any stomach upset that other people are reporting so it's just a case by case situation.Results from using this creatine are very noticeable within a week for me. My muscles feel more firm have more explosiveness in my sets. And also from my experience I feel less sore the day after a good work out. I recommend anybody try it out for themselves.

Expensive but better value for money than smaller dose increments
10 February 2022iHerb Customer

originally posted on iherb.com

The capsules are small and easy to swallow (especially given the dosage; MUCH more convenient than having to take multiple pills per day). I don't really have a sense of whether they're effective and of course I can't actually know what their quality is since I don't have a home chemistry lab.Even though it's quite an investment to buy a bottle of these, I prefer buying two months' worth in one go, rather than having to order more frequently.The automated prompting guidelines wants me to mention "ingredient". I can only assume that the capsules contain what it says on the tin. In comparison with standard form folate (Megafol 5), it does seem to have had a positive impact on my B12 levels and my homocysteine levels have gone from quite high to completely normal. ... MoreThe capsules are small and easy to swallow (especially given the dosage; MUCH more convenient than having to take multiple pills per day). I don't really have a sense of whether they're effective and of course I can't actually know what their quality is since I don't have a home chemistry lab.Even though it's quite an investment to buy a bottle of these, I prefer buying two months' worth in one go, rather than having to order more frequently.The automated prompting guidelines wants me to mention "ingredient". I can only assume that the capsules contain what it says on the tin. In comparison with standard form folate (Megafol 5), it does seem to have had a positive impact on my B12 levels and my homocysteine levels have gone from quite high to completely normal. Take that as you will.

Great product, good choice for your folate needs
6 December 2022Jeyae

originally posted on Target

I got these to take as recommended by my physician because my iron levels were high and he wanted me to take folate.He suggested methylfolate.I like the Thorne brand because it doesn’t have the fillers and and coatings that some brands do.Those can affect absorption of vitamins and supplements.I am taking the Thorne 5-MTHF 5 Mg - Active, Tissue-Ready Folate Supplement - Essential Vitamin B to Support Methylation, Heart Health, Fetal Development, and Nerve Support.There are 60 in a bottle and my dr suggested one capsule daily.I have no aftertaste issues, which is important to me. Some leave a gross taste, or you burp up a nasty urp for hours. Yuck!I take these with food. They aren’t huge and are easy to swallow with water. I don’t notice any stomach ... MoreI got these to take as recommended by my physician because my iron levels were high and he wanted me to take folate.He suggested methylfolate.I like the Thorne brand because it doesn’t have the fillers and and coatings that some brands do.Those can affect absorption of vitamins and supplements.I am taking the Thorne 5-MTHF 5 Mg - Active, Tissue-Ready Folate Supplement - Essential Vitamin B to Support Methylation, Heart Health, Fetal Development, and Nerve Support.There are 60 in a bottle and my dr suggested one capsule daily.I have no aftertaste issues, which is important to me. Some leave a gross taste, or you burp up a nasty urp for hours. Yuck!I take these with food. They aren’t huge and are easy to swallow with water. I don’t notice any stomach discomfort.I’m very happy with these and will be getting another bottle.

Specification

Item formCapsule
Primary supplement typeFolate
Diet typeGluten Free
FlavourFish
Is discontinued by manufacturerNo

Price comparison

Updated about 21 hours ago
Please note: price history and price alerts are not available for some stores, including Amazon.com.au.
Amazon.com.au

$93.95

Thorne Research - Active 5-MTHF 5 mg Folate Vitamin B9-60 Capsules

Delivery $9.99

Affiliate Disclosure: We may receive a small commission for purchases made through this link at no extra cost to you. This helps support our site. Thank you!

eBay.com.au

$93.95

Thorne Active 5-MTHF 5 mg Folate Vitamin B9 - 60 Capsules

Affiliate Disclosure: We may receive a small commission for purchases made through this link at no extra cost to you. This helps support our site. Thank you!

iHerb

$98.51

Thorne, 5-MTHF, 5 mg, 60 Capsules

Free delivery

Price history

Price history

Please note: price history and price alerts are not available for some stores, including Amazon.com.au.

Reviews

Excellent!
4 February 2023

Really like this creatine. I've had others that were very sour and difficult to drink, but not this one! Has no flavor so I am able to mix it with protien shakes or even juice. I also didn't experience any stomach upset that other people are reporting so it's just a case by case situation.Results from using this creatine are very noticeable within a week for me. My muscles feel more firm have more explosiveness in my sets. And also from my experience I feel less sore the day after a good work out. I recommend anybody try it out for themselves.

iHerb Customer originally posted on iherb.com
Expensive but better value for money than smaller dose increments
10 February 2022

The capsules are small and easy to swallow (especially given the dosage; MUCH more convenient than having to take multiple pills per day). I don't really have a sense of whether they're effective and of course I can't actually know what their quality is since I don't have a home chemistry lab.Even though it's quite an investment to buy a bottle of these, I prefer buying two months' worth in one go, rather than having to order more frequently.The automated prompting guidelines wants me to mention "ingredient". I can only assume that the capsules contain what it says on the tin. In comparison with standard form folate (Megafol 5), it does seem to have had a positive impact on my B12 levels and my homocysteine levels have gone from quite high to completely normal. ... MoreThe capsules are small and easy to swallow (especially given the dosage; MUCH more convenient than having to take multiple pills per day). I don't really have a sense of whether they're effective and of course I can't actually know what their quality is since I don't have a home chemistry lab.Even though it's quite an investment to buy a bottle of these, I prefer buying two months' worth in one go, rather than having to order more frequently.The automated prompting guidelines wants me to mention "ingredient". I can only assume that the capsules contain what it says on the tin. In comparison with standard form folate (Megafol 5), it does seem to have had a positive impact on my B12 levels and my homocysteine levels have gone from quite high to completely normal. Take that as you will.

iHerb Customer originally posted on iherb.com
Great product, good choice for your folate needs
6 December 2022

I got these to take as recommended by my physician because my iron levels were high and he wanted me to take folate.He suggested methylfolate.I like the Thorne brand because it doesn’t have the fillers and and coatings that some brands do.Those can affect absorption of vitamins and supplements.I am taking the Thorne 5-MTHF 5 Mg - Active, Tissue-Ready Folate Supplement - Essential Vitamin B to Support Methylation, Heart Health, Fetal Development, and Nerve Support.There are 60 in a bottle and my dr suggested one capsule daily.I have no aftertaste issues, which is important to me. Some leave a gross taste, or you burp up a nasty urp for hours. Yuck!I take these with food. They aren’t huge and are easy to swallow with water. I don’t notice any stomach ... MoreI got these to take as recommended by my physician because my iron levels were high and he wanted me to take folate.He suggested methylfolate.I like the Thorne brand because it doesn’t have the fillers and and coatings that some brands do.Those can affect absorption of vitamins and supplements.I am taking the Thorne 5-MTHF 5 Mg - Active, Tissue-Ready Folate Supplement - Essential Vitamin B to Support Methylation, Heart Health, Fetal Development, and Nerve Support.There are 60 in a bottle and my dr suggested one capsule daily.I have no aftertaste issues, which is important to me. Some leave a gross taste, or you burp up a nasty urp for hours. Yuck!I take these with food. They aren’t huge and are easy to swallow with water. I don’t notice any stomach discomfort.I’m very happy with these and will be getting another bottle.

Jeyae originally posted on Target
Great value
22 September 2023

5-MTHF, or 5-methyltetrahydrofolate, is a bioactive form of folate, a crucial B-vitamin. Many users report improved mood, energy levels, and mental clarity when supplementing with 5-MTHF. It's particularly beneficial for individuals with MTHFR gene mutations, aiding in better folate absorption and utilization. Overall, it's well-regarded for its potential in supporting overall well-being and addressing folate deficiencies effectively. Always consult a healthcare professional before starting any supplement regimen.

iHerb Customer originally posted on iherb.com
It helps my autistic sons
11 August 2023

This product is a game changer ! There are few researches that found folinic acid helpful for autism although when there is no MTHFR genetic mutation. I can't find folinc acid so MTHF5 which is the next stage of folinic acid is a good replacement. It helps my kids to be more focused and calm. It works like a magic , almost immediately, in a few days i can see the improvement. You should take it always with B12 !!!!! Otherwise you can have lack of B12 very quickly.

iHerb Customer originally posted on iherb.com
Natural way to address mood, gut, brain, and heart health
8 December 2022

I got this because I've heard good things about it helping with mood and fatigue. It's supposed to help with heart, gut, and brain health too! I was going to take it and then my husband and I decided to start trying to conceive, which meant I started taking a prenatal vitamin with folic acid in it. I don't want to overdo it on the Vitamin B, so I haven't started taking this yet. But, I plan to once I'm no longer taking the prenatal vitamins. This pill is a methylated version of folate that is more easily absorbed by the body, especially in people with a specific gene mutation called MTHF. I don't have the mutation as far as I know, but figured it'd be worth a shot as a natural way to improve mood and energy. Looking forward to trying it!

rlafler originally posted on Target
Ok
26 May 2023

I recently tried Thorne 5-MTHF capsules, and my experience with this supplement has been quite positive overall.As someone who seeks methylation support, I appreciate the convenience of these capsules. The bottle contains 60 capsules, offering a sufficient supply for a reasonable duration.In terms of potential benefits, 5-MTHF (5-methyltetrahydrofolate) is a bioactive form of folate that plays a crucial role in methylation processes in the body. While it's difficult to evaluate the immediate impact of this supplement, I recognize its potential in supporting methylation pathways and overall health.During the time I took this supplement, I didn't experience any adverse effects or discomfort. However, it's important to note that individual responses may vary, and ... MoreI recently tried Thorne 5-MTHF capsules, and my experience with this supplement has been quite positive overall.As someone who seeks methylation support, I appreciate the convenience of these capsules. The bottle contains 60 capsules, offering a sufficient supply for a reasonable duration.In terms of potential benefits, 5-MTHF (5-methyltetrahydrofolate) is a bioactive form of folate that plays a crucial role in methylation processes in the body. While it's difficult to evaluate the immediate impact of this supplement, I recognize its potential in supporting methylation pathways and overall health.During the time I took this supplement, I didn't experience any adverse effects or discomfort. However, it's important to note that individual responses may vary, and it's advisable to consult with a healthcare professional for personalized guidance.The capsules were easy to swallow, and I appreciated the absence of any noticeable aftertaste or unpleasant odor.Overall, Thorne 5-MTHF capsules provide a convenient way to potentially support methylation processes in the body. With its reliable formulation and bioactive folate form, it may be worth considering for individuals seeking methylation support. However, individual experiences may differ, and it's always recommended to consult with a healthcare professional for personalized recommendations and dosage guidance.

iHerb Customer originally posted on iherb.com
Quarefolic/Extra Folate ingredient has undergone UnNotified change and NO longer effective!!
27 May 2022

Warning ! - The Quarefolic/Extrafolate ingredient sourced by Thorne in this item and others like Methyl Guard etc has undergone an UNNOTIFIED change in formulation / purity / potency/ process and the same is visible in sudden loss of Folate efficacy in this item , methyl guard, methyl guard + etc. which I have been having for more than 5 years +!The messing up of Quarefolic / Extrafolate significantly reduces its absorption ad well as its ability to cross blood brain barrier.I compared this junked folate with Metafolin 5MTHF and could clearly make out that Metafolin is so much better formulated and has excellent cellular absorption as well as purity .I will stay away from Quarefolic / Extrafolate 5MTHF products and recommend you save your hard earned money ... MoreWarning ! - The Quarefolic/Extrafolate ingredient sourced by Thorne in this item and others like Methyl Guard etc has undergone an UNNOTIFIED change in formulation / purity / potency/ process and the same is visible in sudden loss of Folate efficacy in this item , methyl guard, methyl guard + etc. which I have been having for more than 5 years +!The messing up of Quarefolic / Extrafolate significantly reduces its absorption ad well as its ability to cross blood brain barrier.I compared this junked folate with Metafolin 5MTHF and could clearly make out that Metafolin is so much better formulated and has excellent cellular absorption as well as purity .I will stay away from Quarefolic / Extrafolate 5MTHF products and recommend you save your hard earned money from this fraud as well !!Terribly disappointing!!

iHerb Customer originally posted on iherb.com
Teeny tiny capsules
27 December 2022

I’m typically not one to take supplements because there are so many options on the shelves that aren’t vetted. I only tried this by Thorne brand because it is touted as being the best in the business for its pure ingredients and recommended by big well known names. I must say that I am pleased with the results so far. These tiny capsules are easy to swallow and did not upset my stomach or create nausea. Instead, they have improved my mood and cleared up my skin. I can’t tell if it is truly improving my heart health but these couple of benefits alone leave me optimistic it’s providing those benefits too as claimed. My only reservation is that there seems to be inconsistency in the amount to take. The bottle says one capsule up to two times daily but other marketing ... MoreI’m typically not one to take supplements because there are so many options on the shelves that aren’t vetted. I only tried this by Thorne brand because it is touted as being the best in the business for its pure ingredients and recommended by big well known names. I must say that I am pleased with the results so far. These tiny capsules are easy to swallow and did not upset my stomach or create nausea. Instead, they have improved my mood and cleared up my skin. I can’t tell if it is truly improving my heart health but these couple of benefits alone leave me optimistic it’s providing those benefits too as claimed. My only reservation is that there seems to be inconsistency in the amount to take. The bottle says one capsule up to two times daily but other marketing text/images for this product, such as on the Thorne website, I’ve seen it say one capsule up to three times daily. The inconsistency makes me feel uneasy as this seems like something that should be easy to be consistent about throughout. I’m taking one capsule once a day and I’ve seen improvement from that alone.

DearJalen originally posted on Target

Specification

Item formCapsule
Primary supplement typeFolate
Diet typeGluten Free
FlavourFish
Is discontinued by manufacturerNo

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Thorne Research 5-MTHF 5 MG 60 Capsules
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Thorne Research 5-MTHF 5 MG 60 Capsules

Thorne Research 5-MTHF 5 MG 60 Capsules

$93.95

(511 reviews)

Thorne 5-MTHF 5 mg is a highly bioavailable form of folate designed to support healthy methylation, cardiovascular function, and overall well-being. As the active form of folate, 5-MTHF is easily absorbed by the body, making it an excellent choice for individuals who may have difficulty converting synthetic folic acid. This supplement helps support energy production, brain health, and a balanced mood, while also promoting healthy homocysteine levels for cardiovascular support. Ideal for those looking to improve their overall health and nutrient status, Thorne 5-MTHF 5 mg is a convenient and effective way to meet your folate needs. Benefits: Supports cardiovascular health by assisting in the regulation of homocysteine levels. Promotes brain health, mood balance, and cognitive function. Provides a high-potency, bioactive form of folate for enhanced absorption and effectiveness. How to Use: Take 1 capsule daily, preferably with meals, or as directed by your healthcare provider. Use consistently to support cardiovascular and cognitive health. Pair with a balanced diet for optimal folate benefits and overall well-being.

Thorne 5-MTHF 5 mg is a highly bioavailable form of folate designed to support healthy methylation, cardiovascular function, and overall well-being. As the active form of folate, 5-MTHF is easily absorbed by the body, making it an excellent choice for individuals who may have difficulty converting synthetic folic acid. This supplement helps support energy production, brain health, and a balanced mood, while also promoting healthy homocysteine levels for cardiovascular support. Ideal for those looking to improve their overall health and nutrient status, Thorne 5-MTHF 5 mg is a convenient and effective way to meet your folate needs. Benefits: Supports cardiovascular health by assisting in the regulation of homocysteine levels. Promotes brain health, mood balance, and cognitive function. Provides a high-potency, bioactive form of folate for enhanced absorption and effectiveness. How to Use: Take 1 capsule daily, preferably with meals, or as directed by your healthcare provider. Use consistently to support cardiovascular and cognitive health. Pair with a balanced diet for optimal folate benefits and overall well-being.

Thorne Research 5-MTHF 5 MG 60 Capsules

(511 reviews)

Thorne 5-MTHF 5 mg is a highly bioavailable form of folate designed to support healthy methylation, cardiovascular function, and overall well-being. As the active form of folate, 5-MTHF is easily absorbed by the body, making it an excellent choice for individuals who may have difficulty converting synthetic folic acid. This supplement helps support energy production, brain health, and a balanced mood, while also promoting healthy homocysteine levels for cardiovascular support. Ideal for those looking to improve their overall health and nutrient status, Thorne 5-MTHF 5 mg is a convenient and effective way to meet your folate needs. Benefits: Supports cardiovascular health by assisting in the regulation of homocysteine levels. Promotes brain health, mood balance, and cognitive function. Provides a high-potency, bioactive form of folate for enhanced absorption and effectiveness. How to Use: Take 1 capsule daily, preferably with meals, or as directed by your healthcare provider. Use consistently to support cardiovascular and cognitive health. Pair with a balanced diet for optimal folate benefits and overall well-being.

Thorne 5-MTHF 5 mg is a highly bioavailable form of folate designed to support healthy methylation, cardiovascular function, and overall well-being. As the active form of folate, 5-MTHF is easily absorbed by the body, making it an excellent choice for individuals who may have difficulty converting synthetic folic acid. This supplement helps support energy production, brain health, and a balanced mood, while also promoting healthy homocysteine levels for cardiovascular support. Ideal for those looking to improve their overall health and nutrient status, Thorne 5-MTHF 5 mg is a convenient and effective way to meet your folate needs. Benefits: Supports cardiovascular health by assisting in the regulation of homocysteine levels. Promotes brain health, mood balance, and cognitive function. Provides a high-potency, bioactive form of folate for enhanced absorption and effectiveness. How to Use: Take 1 capsule daily, preferably with meals, or as directed by your healthcare provider. Use consistently to support cardiovascular and cognitive health. Pair with a balanced diet for optimal folate benefits and overall well-being.

$93.95 - $98.51

in 3 offers

The lowest price for Thorne Research 5-MTHF 5 MG 60 Capsules right now is $93.95 at Amazon.com.au, compared across 3 retailers.

The all-time low was $37.69 on 27 Nov 2025 — today's price is 149% above the lowest ever. It has been notably cheaper before — worth setting a price alert.

Prices last updated 8 June 2026.

Size:

1 Mg